Protein Alignment step and sh2d3a

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_002665109.4
• Gene: sh2d3a / 100331568
• ZFINID: ZDB-GENE-140401-1
• Length: 806
• Species: Danio rerio
• Alignment Length: 722
• Identity: 131/722 - (18%)
• Similarity: 219/722 - (30%)
• Gaps: 300/722 - (41%)

  Fly    10 SISNWF---------SSLRRQPKNKKCSPGLGGSESV--------GRKQPLQRSCLDLSTTRVGC 57
            |||.|.         |:|.:|      ..||.|.:||        |.:.|..|..:.....:..|
Zfish     5 SISRWLNRIGLPQYTSALEKQ------YYGLEGLQSVTEEDLRLMGVEDPDHRVKILAELQKQQC 63

  Fly    58 D---GCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSC 119
            |   .|.:.......|.:.:|::             :|:.:..|.|.|   .|...|:.|:
Zfish    64 DTENNCTTGTMSSRHSLDLKRTD-------------LFRHSIIPRLRR---RDKRVSASCI---- 108

  Fly   120 NSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPAS---PT 181
                                                             :|.|:...|.|   |.
Zfish   109 -------------------------------------------------QLRPEDHAPCSKHKPR 124

  Fly   182 LSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRT------LIVSRPVELLL 240
            ..:.|...|.|.:.:.::          :.:.|..|.:....|...|:      .:.....|.||
Zfish   125 RRSVTAFISQVFSGLRDM----------DALKKELEEELKLSTEDLRSHAWYHGQLQREAAEQLL 179

  Fly   241 NENGEIIARRS----------------------------PRKSRSNSLGRMLD---------VQN 268
            ..:||.:.|.|                            |::..:..|.:..:         ::.
Zfish   180 GRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIRITLRPKQGYTRELFQFENDQFDNIPALIRF 244

  Fly   269 EIG--------TGGLFMEADPCSKNSLPPPPYIDDMRFIDD-----SSNS---QSESERNSNIHK 317
            .:|        ||.:..:  |.:: :||       :|.|.:     ||::   :|:|:|.| :..
Zfish   245 HVGGRRPISHSTGAVIFQ--PITR-TLP-------LRIISERQAARSSSAHLMRSQSKRRS-LSS 298

  Fly   318 TNKYTSK-NNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLV-------------------- 361
            :.|.|.: |.||..:..||.:||     ..:.|.::.:.|||:.:
Zfish   299 SQKDTLQVNTNNLLRSGSQPANL-----ETVGRPFLQSAQSDSNLRTGVPQSCQSQDSDPAPVSP 358

  Fly   362 ILRRPSKQIKDEL--CEVVSEMEALDVPEDC-----KHSN---KDKQMSIGRKKFNMDPKKGIEY 416
            :.|..|:.:....  |...:...||.|...|     .||.   |..::||.......||:.
Zfish   359 VFRTGSEPVLSPAASCATPAGQSALGVSPLCGSDGQLHSRAPPKPLRISIIFSPTQTDPES---- 419

  Fly   417 LVENRLLRHDPQDV---------AHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNL 472
                     ||.||         ...|.||......|           .|...|:...|.| |:.
Zfish   420 ---------DPADVYGELVPQVPITMLPKGHAARLRA-----------QEQKWKSRARLTD-TSF 463

  Fly   473 ILVQALRQFLWSFRLPGEAQKIDRMMETFAQR----YCQLNPDIFTNTDTCYVL-SFAIIML--- 529
                   .||.:.|:..|..:.:|...:..|:    :|...|.  |.|.:|:.| .|..::|
Zfish   464 -------GFLEAQRVEEERVEEERRSGSELQQEERDWCFERPQ--TETSSCFRLDEFRSLLLPDN 519

  Fly   530 NTSLHN---PSVKD-------KPTVDQFISMN----------------RGIN---------NGGD 559
            |..|..   |.||:       :.|....:|:|                .|:.         :||.
Zfish   520 NRPLDQSVLPKVKELLTQTDARTTALHMLSVNCQVARVTGVTAEQKRIMGVETGLELVTLPHGGQ 584

  Fly   560 LPRGLLE 566
            |.:.|||
Zfish   585 LRQDLLE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	46/222 (21%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
sh2d3a	XP_002665109.4	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910