Protein Alignment step and arfgef1

DIOPT Version :9

• Sequence 1: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Sequence 2: XP_009295669.1
• Gene: arfgef1 / 100329953
• ZFINID: ZDB-GENE-030131-108
• Length: 1870
• Species: Danio rerio
• Alignment Length: 568
• Identity: 152/568 - (26%)
• Similarity: 243/568 - (42%)
• Gaps: 115/568 - (20%)

  Fly   101 ERGSGSDS----------SPSSVCVRCSCNSITKSGDRNET-PTMATP----------------- 137
            |.|.|||:          :|.|.....|......|...|:| .::||.
Zfish   388 EGGLGSDNENVHANGIPGTPISASFTPSLPDDRLSVSSNDTQESVATSGQAPGAKFSHILQKDAF 452

  Fly   138 ---KSDIKIALKP----PPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDV--- 192
               :|..|:::||    ||.|:|..:.  :.|.:..:......:   |.|...|..:..:.:
Zfish   453 LVFRSLCKLSMKPLSDGPPDPKSHELR--SKVLSLQLLLSILQN---AGPIFKTNEMFINAIKQY 512

  Fly   193 ---------TTKVTEVQRLPCDEPNTELISKRT-------------------------EYKHTTI 223
                     .:.|.||..|......|.|.:.:|                         ::|...|
Zfish   513 LCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSYDHKWMVI 577

  Fly   224 TTTTRTLIVSRP-VELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEI--GTGGLFMEADPCSKN 285
            .|.||....::. |::.:|.:.::.|        :|...|:::..::|  |.||..:...|..:.
Zfish   578 QTLTRICADAQSVVDIYVNYDCDLNA--------ANIFERLVNDLSKIAQGRGGHELGTTPLQEL 634

  Fly   286 SLPPPP---YIDDMRFIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLL 347
            :|....   .:..::.:.:.|..|..:        .|..||.......|...|:||..:....:.
Zfish   635 TLRKKGLECLVSILKCMVEWSKDQYVN--------PNSQTSLGRAGQEKPSEQESNESKHPETIN 691

  Fly   348 DRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQ-MSIGRKKFNMDPK 411
            ....||:..|           .....:....::|...|.||..:...:.|: :..|...||..||
Zfish   692 RYGSINSLDS-----------TASSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPK 745

  Fly   412 KGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQ 476
            :||:||.|..:|...|:|:|.||::.|.|:...:|::||:.:..|::|:.|:|...||.....|.
Zfish   746 RGIQYLQEQGMLGTTPEDIAQFLHQEERLDSIQVGEFLGDNDRINKEVMYAYVDQMDFQGKDFVP 810

  Fly   477 ALRQFLWSFRLPGEAQKIDRMMETFAQRY--CQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVK 539
            |||.||..||||||||||||:||.||.||  |.....:|.:.||.|||:::||||.|.||:|.||
Zfish   811 ALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVK 875

  Fly   540 DKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDL 587
            :|.|.:|:|.||||||:..|||...|.::|:.|..:  ||...:..:|
Zfish   876 NKMTKEQYIKMNRGINDSKDLPEEYLSAIYDEIAGK--KISMKETKEL 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	85/182 (47%)
		PH_GRP1-like	592..710	CDD:269954
		PH	596..708	CDD:278594
arfgef1	XP_009295669.1	PLN03076	15..1830	CDD:215560	152/568 (27%)
		DCB	29..210	CDD:292830
		Sec7_N	447..601	CDD:289549	26/158 (16%)
		Sec7	729..913	CDD:279680	85/185 (46%)
		DUF1981	1246..1327	CDD:286414

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820