DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment step and dock9b

DIOPT Version :9

Sequence 1:	NP_001036375.2	Gene:	step / 35425	FlyBaseID:	FBgn0086779	Length:	727	Species:	Drosophila melanogaster
Sequence 2:	XP_021332715.1	Gene:	dock9b / 100151488	ZFINID:	ZDB-GENE-090916-2	Length:	2095	Species:	Danio rerio

Alignment Length:	328	Identity:	70/328 - (21%)
Similarity:	122/328 - (37%)	Gaps:	66/328 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   416 YLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQ 480
            |:.:..|...:|.:....|.:.|.|..|.:......|....|.:        |:.| :|||...|
Zfish    23 YVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPL--------DYEN-VLVQRKTQ 78

  Fly   481 FLWS-----FRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKD 540
            .|..     .:.|.:..:|..:.......|..: ||......:..::...|...|:..|..:.|.
Zfish    79 ILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSV-PDGAEKRASSLLVQECIKTYNSDWHVVNYKY 142

  Fly   541 KPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQD-----DGNDLMHTFFNPDKEGWL 600
            :.....|    |.:.|  .:||.      |.:.:..|::.:|     |...|........|.|||
Zfish   143 EDYSGDF----RQLPN--KVPRP------EKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWL 195

  Fly   601 WKQGGR------YKSWKRRWFILND------NCLYYFEYTTDKEPRGIIPLENISVREIHDRSKP 653
            :|....      .||:|||:|.|..      |..:|.:....|||:|.|.|::......:.:.:.
Zfish   196 YKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRR 260

  Fly   654 HCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQ 718
            ..|||                   .::.|.| |.::|.:|.:..:||..|.: |.|:.| ::.:|
Zfish   261 FAFEL-------------------KMQDKST-YLLAADSEGEMDDWISTLNK-ILHSSF-ELAMQ 303

  Fly   719 RKK 721
            .::
Zfish   304 ERR 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
step	NP_001036375.2	Sec7	397..577	CDD:279680	31/165 (19%)
		PH_GRP1-like	592..710	CDD:269954	32/129 (25%)
		PH	596..708	CDD:278594	31/123 (25%)
dock9b	XP_021332715.1	DUF3398	77..168	CDD:314708	17/103 (17%)
		PH_DOCK-D	184..307	CDD:270087	35/145 (24%)
		C2_Dock-D	650..832	CDD:176079
		DHR2_DOCK9	1634..2050	CDD:212571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910