DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment nolo and Adamts4

DIOPT Version :9

Sequence 1:NP_001036374.1 Gene:nolo / 35424 FlyBaseID:FBgn0051619 Length:1394 Species:Drosophila melanogaster
Sequence 2:NP_076449.1 Gene:Adamts4 / 66015 RGDID:621242 Length:851 Species:Rattus norvegicus


Alignment Length:353 Identity:104/353 - (29%)
Similarity:138/353 - (39%) Gaps:90/353 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 LEQQKRSKVQSAGGGGGAGGGPGQWSSWSDWSTCSRTCDGGIMHQMRRCGSP-----GS-CRGES 112
            ::|.|...:..|||          |..|..|..|||||.||:....|.|..|     |. |.|..
  Rat   523 VDQLKDFNIPQAGG----------WGPWGPWGDCSRTCGGGVQFSSRDCTKPVPRNGGKYCEGRR 577

  Fly   113 TRYRICNMQPCPEQQ--DFRSSQCSAYNDVPYDGTLYK-------WTPHYDYVEP---CALTCRG 165
            |.:|.||.:.||...  .||..||:|||   :...|:|       |.|.|..|.|   |.|||: 
  Rat   578 TPFRSCNTKNCPHGSALTFREEQCAAYN---HRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQ- 638

  Fly   166 HPAHLVEDISRETGDGNAEEAEHYDEQSVIVQLSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKI 230
                     :|..|        :|      ..|..||.|||.|...|..:|:||:|...|||..|
  Rat   639 ---------ARALG--------YY------YVLEPRVADGTPCSPDSSSVCVQGRCIHAGCDRII 680

  Fly   231 GSTKKIDGCGVCGGDGNSCSQPLFNWEMAPMSQCSVTC--------------GSGYKMSRPICRN 281
            ||.||.|.|.||||:|:|||:...:::........|..              |||.|.    ...
  Rat   681 GSKKKFDKCMVCGGNGSSCSKQSGSFKKFRYGYSDVVTIPAGRTHILVRQQGGSGLKS----IYL 741

  Fly   282 RLTNADVDDTLCSVTNRPEASVEQCNTHSCPPRWIADDWS----TCSRLCGHGYRER----MVVC 338
            .|..||....|     ..|.::...:|....|..::..:|    ....|.|||...:    .|:.
  Rat   742 ALKLADGSYAL-----NGEYTLMPSSTDVVLPGAVSLRYSGRTAASETLSGHGPLAQPLTLQVLV 801

  Fly   339 AEESNGIKTRVADIMCR----TPKPPTQ 362
            |.....::.|.:..:.|    ||:||.|
  Rat   802 AGNPQNVRLRYSFFVPRPVPSTPRPPPQ 829

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
noloNP_001036374.1 TSP1 78..124 CDD:214559 20/51 (39%)
TSP1 546..600 CDD:214559
TSP1 750..807 CDD:214559
IGc2 845..902 CDD:197706
PLAC 1355..1384 CDD:285849
Adamts4NP_076449.1 Pep_M12B_propep 92..195 CDD:279848
Reprolysin 232..442 CDD:279729
ZnMc_ADAMTS_like 232..439 CDD:239801
ADAM_CR 452..523 CDD:301627 104/353 (29%)
TSP1 545..589 CDD:214559 17/43 (40%)
ADAM_spacer1 701..816 CDD:283607 20/123 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3538
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.