Protein Alignment nolo and si:ch211-267e7.3

DIOPT Version :10

• Sequence 1: NP_001036374.1
• Gene: nolo / 35424
• FlyBaseID: FBgn0051619
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: XP_073780948.1
• Gene: si:ch211-267e7.3 / 567853
• ZFINID: ZDB-GENE-070912-265
• Length: 975
• Species: Danio rerio
• Alignment Length: 1146
• Identity: 214/1146 - (18%)
• Similarity: 294/1146 - (25%)
• Gaps: 652/1146 - (56%)

  Fly    78 WSSWSDWSTCSRTCDGGIMHQMRRC----------GSPGSCRGESTRYRICNMQPCPEQQ-DFRS 131
            |..||.||||||||.||:..|.|.|          .:...|.|.|.:|::|..||||..: .|:.
Zfish    65 WGEWSSWSTCSRTCGGGVRSQERHCLQQRLTSTQNINSSFCIGPSKQYQLCTNQPCPNSRISFKQ 129

  Fly   132 SQCSAYNDVPYDGTLYKWTPHY--DYV----EPCALTCRGHPAHLVEDISRETGDGNAEEAEHYD 190
            .|||.:|...:....|:|.|.|  ||:    :||.|.|           :..||:.
Zfish   130 HQCSQFNAKAFSRKHYEWVPLYPDDYINISNKPCDLQC-----------TTTTGER--------- 174

  Fly   191 EQSVIVQLSARVQDGTRCRSGSLD-MCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSC----- 249
                  ||.....|||.||.|... :||:|:||.||||.|:.|:|.||.||||||:|.||
Zfish   175 ------QLLVPAHDGTFCRDGIYQGVCIEGQCQVVGCDGKLYSSKTIDKCGVCGGNGASCYRVSG 233

  Fly   250 ----------------------------------------------------------------- 249
                                                                             
Zfish   234 TYRKGITQLGYVFITNIPVGATDIQIIERRKTENILALSDEAGHFFFNGNSVIDNPQNFHVAGTV 298

  Fly   250 -----------------------------------------------------------SQP--- 252
                                                                       .||
Zfish   299 FKYRRPANLFSDGFEYIMAQGPTQQALNVMYYNLNGKMPHITYEYTVPRAPAFPMTSTPEQPQIS 363

  Fly   253 ----------------------------------------------------------------- 252
                                                                             
Zfish   364 NLMSKTSRDSSVAEPKGNTSSTEHNEIGARKQHEKKSNQSSSLVPQDNVDVHEELLWGLQASVNF 428

  Fly   253 ----------------------------------------------------------------- 252
                                                                             
Zfish   429 SELPALVLFRPASEVLQNELDDEIHHLEAQENFGPDSNLIDGDSSSSSDSNTSIPLLKSLLYDGA 493

  Fly   253 ----------------------------------------------------------------- 252
                                                                             
Zfish   494 SWSSRQPCKDSSALSGCSILKLNSSAPLDNSLTLEIYPGSLDLHSPDGEPRTNDSTNHQSNILQL 558

  Fly   253 -----------------------------LFNWEMAPMSQCSVTCGSGYKMSRPICRNRLTNADV 288
                                         ::.|:::..:.||.||.:|...|..:| .:....:|
Zfish   559 HQMEPVQAPHSESNEFEVESLDHDVSMSDMYRWKVSAYAPCSSTCTTGISTSYALC-VKYDGTEV 622

  Fly   289 DDTLCSVTNRPEASVEQCNTHSCPPRWIADDWSTCSRLCGHGYRERMVVCAE-ESNGIKTRVADI 352
            |::.|....|||.:.|.|....|.|||....||.|||.||.|::.|.|.|.: .:.|..:.|.|.
Zfish   623 DESYCDALTRPEPTHEFCTGKECLPRWETSRWSECSRTCGEGFQFRTVRCWKMMAPGFDSSVYDE 687

  Fly   353 MCRT---PKPPTQETCIIEEC-PHWEVEDWTGCSVSC-GQGIQMRGVECKSTDGSLSAK-CDPLT 411
            :|:.   .||.|::.|..:.| |.||:.||:.||..| |:|::.|.|.|     |:.|: |:..|
Zfish   688 LCQAVELQKPMTRKACKSKSCGPQWEISDWSECSARCGGRGVRSRDVRC-----SMEARLCNEST 747

  Fly   412 KPGSMQQCSTGIHCGGSLNKVGGTIIVGSSRSLNERSERQLDSSDADEDNEDENDEGDDVDDLES 476
            ||.|.::|
Zfish   748 KPVSQREC--------------------------------------------------------- 755

  Fly   477 GQDTDDGEGLSYADQPLLYAHRTQSRLNQEAPDEPRTMHLMNGNSNNNFNRGEDESEGPSLDPTY 541
                                                                    |||..|..:
Zfish   756 --------------------------------------------------------EGPPCDRRW 764

  Fly   542 IKDNEWSPCSVTCGEGIRRRTYNCKIFLEYSRTVATVNDSLCEGKKPHDEVERCVEDPCMLPSHG 606
            .. ::|.|||..||||..:|...||
Zfish   765 TV-SDWGPCSGPCGEGRMKRYVVCK---------------------------------------- 788

  Fly   607 FDDQFPRDSIKVGVSEPGKTYVWREQGYTSCSASCLGGVEELIINCVREDNGRVVSPFLCSPETK 671
                                                            ..||:|:|...|.||.|
Zfish   789 ------------------------------------------------NSNGKVISDGQCDPELK 805

  Fly   672 PEARVRTCNDRPCPPRWNYSDYTPCSKSCGIGIKTREVQCIHEVTRGGDNTMV---VPNSMCPQP 733
            |.| |..|.|:.||..|...::..|:.:||.|:|||:|.|      .|....|   .|..||.:.
Zfish   806 PLA-VHPCGDKNCPAHWVEQEWEQCNSTCGRGVKTRQVVC------AGLEAGVFKEFPERMCDRA 863

  Fly   734 -PPADRQYCNVLDCPVRWEVGEWSKCSHTCGYGFKDRKVECKQIMAQEHKIE---RPESMCPSAK 794
             .|||...|....|. :|....||:||.|||.|.:.|:|:|.|.....|..:   |||:
Zfish   864 LRPADTAACFERPCS-KWFTTSWSQCSKTCGIGVRVREVKCYQGEELGHSCDTTLRPEA------ 921

  Fly   795 PADKKPCNVKPCPPEDP-------KP------VIQINNSTH 822
               ::.|.|:||..|.|       ||      |:::...||
Zfish   922 ---RQSCEVQPCTTEPPADDACQDKPTANCALVLRVKLCTH 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nolo	NP_001036374.1	TSP1	78..124	CDD:214559	23/55 (42%)
		TSP1_ADAMTS	256..311	CDD:465950	16/54 (30%)
		TSP1_ADAMTS	315..370	CDD:465950	20/58 (34%)
		TSP1_ADAMTS	373..420	CDD:465950	19/48 (40%)
		TSP1	546..600	CDD:214559	11/53 (21%)
		TSP1_ADAMTS	629..684	CDD:465950	13/54 (24%)
		TSP1_ADAMTS	688..746	CDD:465950	19/61 (31%)
		TSP1_ADAMTS	750..806	CDD:465950	19/58 (33%)
		Ig	845..914	CDD:472250
		Ig strand B	848..852	CDD:409353
		Ig strand C	861..865	CDD:409353
		Ig strand E	883..887	CDD:409353
		Ig strand F	897..902	CDD:409353
		TSP1_ADAMTS	1157..1227	CDD:465950
		TSP1_ADAMTS	1289..1343	CDD:465950
		PLAC	1355..1384	CDD:462560
si:ch211-267e7.3	XP_073780948.1	None