DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nolo and Adamtsl5

DIOPT Version :9

Sequence 1:	NP_001036374.1	Gene:	nolo / 35424	FlyBaseID:	FBgn0051619	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	XP_038934914.1	Gene:	Adamtsl5 / 314626	RGDID:	1305607	Length:	714	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	76/247 - (30%)
Similarity:	95/247 - (38%)	Gaps:	65/247 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CLLDTQAAWAKKLNASQAFDDTWNTAS-DLENELEQQKRSKVQSAGGGGGAGGGPGQWSSWSDWS 85
            |||.||.:...:|.....| ..|...| ||.                  ||..|||:|:.|..||
  Rat   162 CLLGTQCSLRPRLFPPLLF-LLWILLSCDLR------------------GAAQGPGEWTLWGSWS 207

  Fly    86 TCSRTCDGGIMHQMRRC---GSPGSCRGESTRYRICNM----------QPCPEQQ-DFRSSQCSA 136
            .||.:|..|:..:.|.|   .....|.|:|..||:|.:          |.||... .||..|||.
  Rat   208 RCSSSCGRGVSVRRRHCVRLPEEELCWGDSHEYRVCQLPFYPSTFMLTQDCPPGAIPFRDLQCSL 272

  Fly   137 YNDVPYDGT--LYKWTPHYDYVEPCALTC--RGHPAHLVEDISRETGDGNAEEAEHYDEQSVIVQ 197
            ||..|..||  .|:|.|.:.....|.|.|  .||                           ....
  Rat   273 YNGHPVLGTQKTYQWVPFHGAPNLCDLNCLAEGH---------------------------AFYH 310

  Fly   198 LSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSC 249
            ...||.|||.|..|:..:|:.|:|...|||..:||....|.||:|||..:||
  Rat   311 SFGRVLDGTPCTPGTQGLCVAGRCLSAGCDGLLGSGTLEDRCGLCGGANDSC 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nolo	NP_001036374.1	TSP1	78..124	CDD:214559	17/58 (29%)
		TSP1	546..600	CDD:214559
		TSP1	750..807	CDD:214559
		IGc2	845..902	CDD:197706
		PLAC	1355..1384	CDD:285849
Adamtsl5	XP_038934914.1	TSP1	200..246	CDD:214559	16/45 (36%)
		ADAM_spacer1	444..541	CDD:368694
		NTR_like	608..707	CDD:239600
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900