DRSC/TRiP Functional Genomics Resources

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Protein Alignment nolo and Adamts14

DIOPT Version :9

Sequence 1:NP_001036374.1 Gene:nolo / 35424 FlyBaseID:FBgn0051619 Length:1394 Species:Drosophila melanogaster
Sequence 2:NP_001376166.1 Gene:Adamts14 / 309837 RGDID:1308899 Length:1203 Species:Rattus norvegicus


Alignment Length:521 Identity:133/521 - (25%)
Similarity:192/521 - (36%) Gaps:188/521 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 RSKVQSAGGGGGAGGGPGQWSSWSDWSTCSRTCDGGIMHQMRRCGSPGS------CRGESTRYRI 117
            :|..|:.|..||       ||||:::.:|||:|.||:..:.|.|.:|..      |.|....|:|
  Rat   527 KSPEQTYGQDGG-------WSSWTNFGSCSRSCGGGVRSRSRSCDNPPPAYGGRLCSGPMFEYQI 584

  Fly   118 CNMQPCPEQ-QDFRSSQCSAYND-VPYDGTLYKWTPHYDYVEP------CALTCRGHPAHLVEDI 174
            ||.:.||.. :|||:.||:..|. ..:....:.|.|:    ||      |.|.|:          
  Rat   585 CNSEDCPGPFEDFRAQQCAKRNSYYTHQDAKHSWLPY----EPDSEAQKCELICQ---------- 635

  Fly   175 SRETGDGNAEEAEHYDEQSVIVQLSARVQDGTRCR-SGSLDMCIQGKCQRVGCDLKIGSTKKIDG 238
            |.:|||              :|.::..|.|||||. .....:|.:|:|...|||.::||.|..|.
  Rat   636 SADTGD--------------VVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKTDDK 686

  Fly   239 CGVCGGDGNSC------------------------------------------------------ 249
            |||||||.:.|                                                      
  Rat   687 CGVCGGDNSHCRTVKGTLGKASKQAAALKQVQIPAGARHIQIELLEKAPRRIAVKNQVTGSFILN 751

  Fly   250 -------------------------------SQPL------------------------------ 253
                                           :.||                              
  Rat   752 PKGKEASSRTFTALGLEWEHAAEDTKDSLKTNGPLPEAIAVLVLPPAEGKPRGSLAYKYVIHEDL 816

  Fly   254 ----------------FNWEMAPMSQCSVTCGSGYKMSRPICRNRLTNADVDDTLCSVTNRPEAS 302
                            :.|.:...|.||..||.|.:.::..||:|..:..|...||....||:|.
  Rat   817 LPLIGSNNVLLEEMDSYEWALKSWSPCSKACGGGIQFTKYGCRHRRDHHMVQRHLCDHKKRPKAI 881

  Fly   303 VEQCNTHSCP-PRWIADDWSTCSRLCGH-GYRERMVVC-AEESNGIKTRVADIMCRTPKPPTQET 364
            ..:||.|.|| |.|:.::|..|||.||. |.:.|.|.| ...|||....:....|...:|..:..
  Rat   882 RRRCNQHPCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKRP 946

  Fly   365 CIIEECP-HWEVEDWTGCSVSCGQGIQMRGVECKSTDGSLSAKCDPLTKPGSMQQCSTGIHCGGS 428
            |:...|| .|....|:.||.:||:|||.|.|.|:::..:| ..|:.: ||.:::.||... |||.
  Rat   947 CLRVPCPAQWRTGAWSQCSATCGKGIQQRQVVCRNSSSAL-GPCEGV-KPDTVRICSQPA-CGGD 1008

  Fly   429 L 429
            |
  Rat  1009 L 1009

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
noloNP_001036374.1 TSP1 78..124 CDD:214559 19/51 (37%)
TSP1 546..600 CDD:214559
TSP1 750..807 CDD:214559
IGc2 845..902 CDD:197706
PLAC 1355..1384 CDD:285849
Adamts14NP_001376166.1 Pep_M12B_propep 68..191 CDD:396235
ZnMc_ADAMTS_like 243..441 CDD:239801
ADAM_CR_2 456..525 CDD:407643
TSP1 539..591 CDD:214559 19/51 (37%)
ADAM_spacer1 698..813 CDD:368694 2/114 (2%)
TSP1_ADAMTS 835..890 CDD:408800 19/54 (35%)
TSP1_ADAMTS 895..952 CDD:408800 17/56 (30%)
TSP1_ADAMTS 956..1005 CDD:408800 18/51 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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