DRSC/TRiP Functional Genomics Resources

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Protein Alignment nolo and Adamts15

DIOPT Version :9

Sequence 1:NP_001036374.1 Gene:nolo / 35424 FlyBaseID:FBgn0051619 Length:1394 Species:Drosophila melanogaster
Sequence 2:NP_001100280.1 Gene:Adamts15 / 300474 RGDID:1309770 Length:950 Species:Rattus norvegicus


Alignment Length:464 Identity:128/464 - (27%)
Similarity:178/464 - (38%) Gaps:155/464 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 GQWSSWSDWSTCSRTCDGGIMHQMRRCGSPGS------CRGESTRYRICNMQPCPEQ---QDFRS 131
            |.|:.|..:..|||||.||:....|:|.:|..      |.|...:||.||::|||..   :.||.
  Rat   517 GSWAKWEPYGPCSRTCGGGVQLARRQCSNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFRE 581

  Fly   132 SQCSAYNDVPYDG---TL-YKWTPHYDYVEP---CALTCRGHPAHLVEDISRETGDGNAEEAEHY 189
            .||.|:|...:..   || ..|.|.|..|.|   |.|.||.:            |.|        
  Rat   582 EQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRAN------------GTG-------- 626

  Fly   190 DEQSVIVQLSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSC----- 249
                ....|:.:|.|||.|...|..:|:||||.:.|||..:||.||.|.|||||||..||     
  Rat   627 ----YFYVLAPKVVDGTLCTPDSTSVCVQGKCIKAGCDGNLGSKKKFDKCGVCGGDNKSCKRVTG 687

  Fly   250 --SQPL--FNWEMA-PMSQCSVTCGS-GYK----------------------------------- 273
              ::|:  :|:.:| |....|:.... |||                                   
  Rat   688 LFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVV 752

  Fly   274 ------------------MSRPICR---------NRLTNADV----------------------- 288
                              .||||..         .::|...|                       
  Rat   753 KGSVLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSRPKDPRG 817

  Fly   289 ----DDTLCSVTNRPEASVEQCNTHSCPPRWIADDWSTCSRLCGHGYRERMVVCAEE--SNGIKT 347
                .:::.|::|:    |||.:... |.||:|.:|..||..||.|.::|.|.|.:.  ..||..
  Rat   818 PPVLRNSVLSLSNQ----VEQPDNRP-PARWVAGNWGPCSVSCGSGLQKRAVDCRDSPGQQGISA 877

  Fly   348 RVADIMCRTPKPPTQETCIIEECPHWEVEDWTGCSVSCGQGIQMRGVECKSTDGSLSAK--CDPL 410
                  |.....|.::....|.||.||:.:|:.||.|||:|.:.|.::|....|.|.|:  ||..
  Rat   878 ------CDVDHRPVEKRACGEPCPTWELGNWSPCSKSCGRGFKRRPLKCVGHGGRLLARDQCDLR 936

  Fly   411 TKPGSMQQC 419
            .||..:..|
  Rat   937 RKPQELDFC 945

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
noloNP_001036374.1 TSP1 78..124 CDD:214559 19/51 (37%)
TSP1 546..600 CDD:214559
TSP1 750..807 CDD:214559
IGc2 845..902 CDD:197706
PLAC 1355..1384 CDD:285849
Adamts15NP_001100280.1 Pep_M12B_propep 42..157 CDD:279848
Reprolysin 218..427 CDD:279729
ZnMc_ADAMTS_like 218..424 CDD:239801
ADAM_CR 437..506 CDD:301627
TSP1 519..571 CDD:214559 19/51 (37%)
ADAM_spacer1 683..801 CDD:283607 14/117 (12%)
TSP1 846..895 CDD:214559 14/54 (26%)
TSP1 897..950 CDD:214559 19/49 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3538
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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