Protein Alignment nolo and adamts8

DIOPT Version :9

• Sequence 1: NP_001036374.1
• Gene: nolo / 35424
• FlyBaseID: FBgn0051619
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: XP_002940685.2
• Gene: adamts8 / 100497759
• XenbaseID: XB-GENE-994782
• Length: 956
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 147/578 - (25%)
• Similarity: 206/578 - (35%)
• Gaps: 194/578 - (33%)

  Fly     3 VNMNWTSPKIW---AALFVTTL-------CLLD--------------TQAAWAKKLNASQAFDDT 43
            :.:|.|.|  |   :|:.:|..       ||||              |.|.:.......|.|...
 Frog   412 LQLNKTVP--WSECSAMHLTEFFDSGHGDCLLDAPSKSIELPNGLPGTSALYDLDSQCRQVFGKE 474

  Fly    44 WNTASDLENELEQ----------QKRSKVQSAGGG-GGAGGGP---------------------- 75
            :   |...|.||:          |::::..:..|. ..|.|.|
 Frog   475 F---SHCPNTLEKDVCSQLWCRIQEKNECHTKNGSLPWADGTPCGDNHMCSDGVCVKEDIVVRPK 536

  Fly    76 ----GQWSSWSDWSTCSRTCDGGIMHQMRRCGSP-----GS-CRGESTRYRICNMQPCP-EQQDF 129
                |.|.||..|..|||||.||:....|.|..|     |. |:|:...|..||:|.|| .:..|
 Frog   537 VPVDGSWGSWGPWGECSRTCGGGVRFSYRDCNDPVPQNGGKYCKGQRAMYESCNIQECPVHELSF 601

  Fly   130 RSSQCSAYNDVPY---DGTLYKWTPHY---DYVEPCALTCRGHPAHLVEDISRETGDGNAEEAEH 188
            |..||..||...|   :|||.:|.|.|   .|.:.|.|.|                     :|..
 Frog   602 REEQCMKYNSYNYTDEEGTLLQWIPKYSGVSYRDRCKLVC---------------------QARD 645

  Fly   189 YDEQSVIVQLSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSC---- 249
            .:|..|   ..::|.|||.|...||.:|:||:|...|||..:||:||:|.||||||||:||
 Frog   646 RNEFKV---FQSKVVDGTLCEPDSLKVCVQGQCISAGCDHILGSSKKMDKCGVCGGDGSSCRKIT 707

  Fly   250 --------------SQP--LFNWEMAPMSQCSVTCGSGYKMSRPICRNRLTNADVD--------- 289
                          |.|  ..|.::...|...:.....|...:....:.|.|.|..
 Frog   708 DSFNKSKYGYTDIVSIPAGATNIDIKKRSHRGIIYDGNYLAIKKADGSYLLNGDFAVSYMEQDLH 772

  Fly   290 ---------------DTLCSVTNRPEA-------------------------SVEQCNT------ 308
                           :.:.|....||:                         :|....|
 Frog   773 LRGIVLKYSGSLTTLERIRSFYPLPESLTIQLLSVLAETLPPKVKYTFFIPKNVSYAKTKPKLSH 837

  Fly   309 HSCPP----RWIADDWSTCSRLCGHGYRERMVVCAEESNGIKTRVADIMCRTPKPPTQETCIIEE 369
            ||..|    :|...||..||:.||.|::.|.|.|.:...|    .:|...:..:|.....|....
 Frog   838 HSLRPLLTSQWTFRDWFPCSKSCGFGWQRRAVECQDVEGG----PSDQCPQELRPIDIRPCGDLP 898

  Fly   370 CPHWEVEDWTGCSVSCGQGIQMRGVECKSTDG--SLSAKCDPLTKPGS------MQQC 419
            ||.|.|..|:.||.|||:|::.:.|.|....|  :...||||..:|..      :::|
 Frog   899 CPIWRVGGWSPCSQSCGEGVRSQRVFCVDYTGRETEEEKCDPGKRPAKPVNSCILEEC 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nolo	NP_001036374.1	TSP1	78..124	CDD:214559	21/51 (41%)
		TSP1	546..600	CDD:214559
		TSP1	750..807	CDD:214559
		IGc2	845..902	CDD:197706
		PLAC	1355..1384	CDD:285849
adamts8	XP_002940685.2	Pep_M12B_propep	33..142	CDD:366707
		ZnMc_ADAMTS_like	236..441	CDD:239801	7/30 (23%)
		ADAM_CR_2	455..527	CDD:375321	13/74 (18%)
		TSP1	543..595	CDD:214559	21/51 (41%)
		ADAM_spacer1	704..823	CDD:368694	11/118 (9%)
		TSP1	846..900	CDD:214559	15/57 (26%)
		TSP1	905..942	CDD:214559	14/36 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11725
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000