DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nolo and XB995277

DIOPT Version :9

Sequence 1:	NP_001036374.1	Gene:	nolo / 35424	FlyBaseID:	FBgn0051619	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	XP_031760531.1	Gene:	XB995277 / 100487633	XenbaseID:	XB-GENE-995278	Length:	488	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	68/250 - (27%)
Similarity:	85/250 - (34%)	Gaps:	65/250 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NWTSPKIWAALFVTTLCLLDTQAAWAKKLNASQAFDDTWNTASDLENELEQQKRSKVQSAGGGGG 70
            ||.....:...|:...|  |||..                             .|..||   ||.
Frog     5 NWFLAVFFITFFIHADC--DTQVT-----------------------------DSMYQS---GGI 35

  Fly    71 AGGGPGQWSSWSDWSTCSRTCDGGIMHQMRRC---GSPGSCRGESTRYRICNMQPCPEQQ-DFRS 131
            .....|||::|:.|::.|.||..|:..:.|||   .....|.||..:||.|....|||.. .||.
Frog    36 TRPSKGQWTAWASWTSSSSTCGNGVAVRTRRCLRVTRMDRCAGEQRQYRSCQSGICPEDALPFRD 100

  Fly   132 SQCSAYNDVPYDGTL--YKWTPHYDYVEPCALTCRGHPAHLVEDISRETGDGNAEEAEHYDEQSV 194
            .||:.||..|..|:.  |||.|.|.....|.|.|..            .|..
Frog   101 LQCALYNYRPIPGSQRGYKWVPFYGAPTACHLNCLA------------VGQN------------- 140

  Fly   195 IVQLSARVQDGTRCRSGSLDMCIQGKCQRVGCDLKIGSTKKIDGCGVCGGDGNSC 249
            ......||.|||.|...|...||.|:|.:..|:....|....:.||.|....|:|
Frog   141 FYYTFGRVLDGTSCGPNSNGTCINGQCLKADCNGIFTSEVSKESCGKCQEQQNTC 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nolo	NP_001036374.1	TSP1	78..124	CDD:214559	16/48 (33%)
		TSP1	546..600	CDD:214559
		TSP1	750..807	CDD:214559
		IGc2	845..902	CDD:197706
		PLAC	1355..1384	CDD:285849
XB995277	XP_031760531.1	TSP1	<56..92	CDD:214559	11/35 (31%)
		ADAM_CR_2	99..168	CDD:407643	26/93 (28%)
		ADAM_spacer1	207..309	CDD:368694
		NTR	379..479	CDD:396359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000