DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF2 and AT5G25230

DIOPT Version :9

Sequence 1:	NP_525105.2	Gene:	eEF2 / 35422	FlyBaseID:	FBgn0000559	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001318643.1	Gene:	AT5G25230 / 832594	AraportID:	AT5G25230	Length:	973	Species:	Arabidopsis thaliana

Alignment Length:	864	Identity:	333/864 - (38%)
Similarity:	507/864 - (58%)	Gaps:	55/864 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKA---GETRFTDTRKDEQERCITIKS 72
            |||.....:||::::.|:.|||:...|.||.:...::...|   ...|:||||.|||||.|:||:
plant   116 GLMSNPALVRNVALVGHLQHGKTVFMDMLVEQTHRMSTFNAENDKHMRYTDTRVDEQERNISIKA 180

  Fly    73 TAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVS 137
            ..:|:..|            |.|.   |.:|.|::|:||:|:||.|:||:||:.|||:.:||...
plant   181 VPMSLVLE------------DSRS---KSYLCNIMDTPGNVNFSDEMTASLRLADGAVFIVDAAQ 230

  Fly   138 GVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVN--VIIATYNDDG 200
            ||.|.||..:|.||.:.:..::.:||:||.:.||:|...:.|...:..:|.:|  :..|:.|...
plant   231 GVMVNTERAIRHAIQDHLPIVVVINKVDRLITELKLPPRDAYYKLRYTIEVINNHISAASTNAAD 295

  Fly   201 GPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKI--DVVKLMNRLWGENFFNAKTKKW 263
            .|:    :||:.|:|.|.||..||:|||:.|:.||::...:  ||.|..:||||:.:::..|:.:
plant   296 LPL----IDPAAGNVCFASGTAGWSFTLQSFARMYAKLHGVAMDVDKFASRLWGDVYYHPDTRVF 356

  Fly   264 QKQKE-ADNKRSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMR 327
            ..... ...:|:|..:||:|:||::..::...|:.:.|.|.::||||.:.....:.:.||:....
plant   357 NTSPPVGGGERAFVQFILEPLYKIYSQVIGEHKKSVETTLAELGVTLSNSAYKLNVRPLLRLACS 421

  Fly   328 TWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSD 392
            :...:......|:..|:|||..|...:::..|.|..|.....::..|||.||||:.::|:.|.||
plant   422 SVFGSASGFTDMLVKHIPSPREAAARKVDHSYTGTKDSPIYESMVECDPSGPLMVNVTKLYPKSD 486

  Fly   393 KGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICG 457
            ...|..||||::|::.|||..|::|..|:|..:||:..|.:.:..:...||...:...|.|:...
plant   487 TSVFDVFGRVYSGRLQTGQSVRVLGEGYSPEDEEDMTIKEVTKLWIYQARYRIPVSSAPPGSWVL 551

  Fly   458 LVGVDQFLVKTGTITTF---KDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPM 519
            :.|||..::||.|:...   :|.:..:.:||:..|||:.|.||.||::|||:||||::::||.|:
plant   552 IEGVDASIMKTATLCNASYDEDVYIFRALKFNTLPVVKTATEPLNPSELPKMVEGLRKISKSYPL 616

  Fly   520 VQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNK 584
            ....:||||||.|.|.|||:|:..:|||.|.::.:.:|.:|||||:.|||.|.|...|.:::|||
plant   617 AITKVEESGEHTILGTGELYLDSIIKDLRELYSEVQVKVADPVVSFCETVVESSSMKCFAETPNK 681

  Fly   585 HNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFIL 649
            .|:|.|.|.|:..||.|||:||.||..........:...|||:|:..||.||.||||..|.|.:|
plant   682 KNKLTMIAEPLDRGLAEDIENGVVSIDWNRVQLGDFFRTKYDWDLLAARSIWAFGPDKQGTNILL 746

  Fly   650 DCTKSVQ----YLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPT 710
            |.|...:    .:..:|||:|.||||.::||.|.||.:|.|:|.|.|..:..:.:|||.||:|||
plant   747 DDTLPTEVDRNLMMGVKDSIVQGFQWGAREGPLCDEPIRNVKFKIVDARIAPEPLHRGSGQMIPT 811

  Fly   711 TRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLP 775
            .||..|:|.:.|.||||||||..|||.|...|..||.||:||||:|..:....|||.::|||:||
plant   812 ARRVAYSAFLMATPRLMEPVYYVEIQTPIDCVTAIYTVLSRRRGYVTSDVPQPGTPAYIVKAFLP 876

  Fly   776 VNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGD---------PSEPS-----SKPYAIVQDTRK 826
            |.|||||..|||.:|.||||...|||||.::|||         |.||:     ::.:.:  .||:
plant   877 VIESFGFETDLRYHTQGQAFCLSVFDHWAIVPGDPLDKAIQLRPLEPAPIQHLAREFMV--KTRR 939

  Fly   827 RKGLKEGLPDLS--QYLDK 843
            |||:.|   |:|  ::.|:
plant   940 RKGMSE---DVSGNKFFDE 955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	333/864 (39%)
		EF2	20..236	CDD:206672	81/220 (37%)
		EF2_snRNP_like_II	380..474	CDD:293901	32/93 (34%)
		EF2_snRNP_III	489..560	CDD:293918	35/70 (50%)
		aeEF2_snRNP_like_IV	560..732	CDD:238839	83/175 (47%)
		eEF2_snRNP_like_C	728..807	CDD:239763	45/78 (58%)
AT5G25230	NP_001318643.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100212
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720