Protein Alignment eEF2 and eef2a.1

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001038626.3
• Gene: eef2a.1 / 792182
• ZFINID: ZDB-GENE-050522-500
• Length: 854
• Species: Danio rerio
• Alignment Length: 864
• Identity: 602/864 - (69%)
• Similarity: 703/864 - (81%)
• Gaps: 32/864 - (3%)

  Fly     1 MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQE 65
            |.||.||:||..||||.||||||||...|||||||||.|||||||::.|:||||||.|||:||||
Zfish     1 MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSKAGIVSSARAGETRFMDTRRDEQE 65

  Fly    66 RCITIKSTAISMYFEVEEKDLVFITHPDQREKECK---GFLINLIDSPGHVDFSSEVTAALRVTD 127
            ||||||||.||:::|:.||||.||       ||||   |||:||||||||||||||||||||:||
Zfish    66 RCITIKSTTISIFYELAEKDLAFI-------KECKDGSGFLLNLIDSPGHVDFSSEVTAALRITD 123

  Fly   128 GALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVI 192
            |||:|||||||||:||||||||||.|||||:|.:||||||||||||..|||||.||||||.|||.
Zfish   124 GALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVT 188

  Fly   193 IATY-NDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKF-------------KI-D 242
            |:|| .|:.||||.|.:||..|::.|||||||||||||||:|:|.:||             |: |
Zfish   189 ISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVED 253

  Fly   243 VVKLMNRLWGENFFNAKTKKWQKQKEA-DNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLE 303
            ::|   ||||:::|::.|.|:.:...: |.|   |:|...:||||:||||||||:||||...|:|
Zfish   254 MIK---RLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIE 315

  Fly   304 KIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAA 368
            |:|:.|..|||:|:||.|||.|||.||||||||||||.|||||||.||.||.|:|||||.|||||
Zfish   316 KMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAA 380

  Fly   369 IAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAI 433
            :.:|:|||..|||||||||:||||||.||||||||:|.|:||...||||||:||||:||||.|.|
Zfish   381 MGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKEEDLYLKPI 445

  Fly   434 QRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPK 498
            |||:||||||||.|||||.|||.||:|||||||||||||||..|:||:||||||||.|||:||..
Zfish   446 QRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPAVRVSVEVM 510

  Fly   499 NPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVV 563
            :||||||||||||.|||||||:|||||::||||||||||||||||||||||||||||||||||..
Zfish   511 DPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFA 575

  Fly   564 SYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYD 628
            |||||||:.|.|:||:|:||||:||.|||.|:.|||.||||.|.|:|..|..|||:||:|.|.::
Zfish   576 SYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWE 640

  Fly   629 VTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDV 693
            ||||||||||||:|||||.::|.||.|||||||||||:||||||::||:|..||:||:||.|:|.
Zfish   641 VTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFEIHDA 705

  Fly   694 TLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFE 758
            ||.:.|||||.||||..|||.||...:||:|||.||:||.|:|||:..:|.|||.|.||||.||.
Zfish   706 TLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPKSVIGNIYGELVRRRGVVFS 770

  Fly   759 ENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQD 823
            |:||:|||::::||||||:||||||||||..|.||||.||||||||:|||||.:|:||...|:.|
Zfish   771 ESQVMGTPVYLLKAYLPVSESFGFTADLRFYTSGQAFSQCVFDHWQILPGDPLDPTSKAAHIMAD 835

  Fly   824 TRKRKGLKEGLPDLSQYLD 842
            .||.|||.|.:|.|..|||
Zfish   836 IRKSKGLDEAIPALHCYLD 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	602/864 (70%)
eef2a.1	NP_001038626.3	None