Protein Alignment eEF2 and eftud2

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001025537.1
• Gene: eftud2 / 594937
• XenbaseID: XB-GENE-972643
• Length: 974
• Species: Xenopus tropicalis
• Alignment Length: 868
• Identity: 327/868 - (37%)
• Similarity: 510/868 - (58%)
• Gaps: 56/868 - (6%)

  Fly     4 FTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETR--------FTDTR 60
            :.:|.:..|||....|||:::..|:.|||:...|.|:.:.       ..|.|        :||..
 Frog   116 YEMDFLADLMDNPELIRNVTLCGHLHHGKTCFVDCLIEQT-------HPEIRKRHDQDLCYTDIL 173

  Fly    61 KDEQERCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRV 125
            ..||||.:.:|||.::            |..||.:|   |.:|.|::|:||||:||.||||..|:
 Frog   174 FTEQERGVGMKSTPVT------------IVVPDTKE---KSYLFNIMDTPGHVNFSDEVTAGFRI 223

  Fly   126 TDGALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVN 190
            :||.::.:|...||.:.||.:::.|:.||:...:.:||:||.:|||:|...:.|...:.||:.||
 Frog   224 SDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVN 288

  Fly   191 VIIATYNDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKF-KIDVVKLMNRLWGEN 254
            .:::.|:.|    ..:.:.|..|:|.|.|..:...|||..|:::|::.: .|:..:...||||:.
 Frog   289 GLLSMYSTD----ENLILSPLLGNVCFASSQYSICFTLGSFAKIYADTYGDINYQEFAKRLWGDI 349

  Fly   255 FFNAKTKKW-QKQKEADNKRSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDG 318
            :||.||:|: :|...:.::|||..::|:|:||:...::......:...||::|:.|..|:...:.
 Frog   350 YFNPKTRKFTKKAPTSSSQRSFVEFVLEPLYKILAQVVGDVDTTLPQTLEELGIHLTKEELKLNI 414

  Fly   319 KALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMY 383
            :.||:.|...:.......:.|...|:|||....:.::|..|.|..|.|...|:..||||||||.:
 Frog   415 RPLLRLVCNRFFGEFTGFVDMCVQHIPSPKAGARAKIEHTYAGGIDCELGEAMSECDPDGPLMCH 479

  Fly   384 ISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIE 448
            .:||..|.|..:|:||||:.:|.:..||..:::|.|||...:||.....:.|..:.:.||...:.
 Frog   480 TTKMYSTDDGVQFHAFGRLLSGTIHAGQPVKVLGENYTLEDEEDSQVCTVGRLWVSVARYHIEVN 544

  Fly   449 DVPSGNICGLVGVDQFLVKTGTITT---FKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLVEGL 510
            .||:||...:.||||.:|||.|||.   .::|...:.:||:.:.|:::||||.||::|||:::||
 Frog   545 RVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGL 609

  Fly   511 KRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQ 575
            :::.||.|.:...:||||||:|.|.|||:|:..:.||.:.::.|.:|.:||||::.|||.|.|..
 Frog   610 RKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSL 674

  Fly   576 MCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGP 640
            .|.:::|||.|::.|.|.|:..||.|||:|..|......|....:...|||:|:..||.||.|||
 Frog   675 KCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQISWNRKKLGEFFQTKYDWDLLAARSIWAFGP 739

  Fly   641 DGTGPNFILDCTKSVQ----YLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIH 701
            |.||||.::|.|...:    .|:.:|||:|.||||.::||.|.||.:|.|:|.|.|..:..:.:|
 Frog   740 DTTGPNILVDDTLPSEVDKALLSSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVIAQEPLH 804

  Fly   702 RGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTP 766
            |||||||||.||.:|:|.:.|.||||||.|..|:|.|...|..:|.||.||||||.::..:.|:|
 Frog   805 RGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSP 869

  Fly   767 MFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGD---------PSEPSSKPY---A 819
            ::.:||::|..:||||..|||::|.||||...||.|||::|||         |.||...|:   .
 Frog   870 LYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIIIRPLEPQPAPHLARE 934

  Fly   820 IVQDTRKRKGLKEGLPDLSQYLD 842
            .:..||:||||.|.: .:|::.|
 Frog   935 FMIKTRRRKGLSEDV-SISKFFD 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	327/868 (38%)
eftud2	NP_001025537.1	EFTUD2	4..112	CDD:464968
		PRK13351	124..956	CDD:481252	325/858 (38%)