Protein Alignment eEF2 and eef2.2

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001015785.1
• Gene: eef2.2 / 548502
• XenbaseID: XB-GENE-5771153
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 866
• Identity: 681/866 - (78%)
• Similarity: 750/866 - (86%)
• Gaps: 29/866 - (3%)

  Fly     1 MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQE 65
            |||||||:||.:||||.|||||||||||||||||||||||.||||||.|:|||||||||||||||
 Frog     1 MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQE 65

  Fly    66 RCITIKSTAISMYFEVEEKDLVFITHPDQREKECK---GFLINLIDSPGHVDFSSEVTAALRVTD 127
            |||||||||||:|:|:.|.||.||       |:||   |||||||||||||||||||||||||||
 Frog    66 RCITIKSTAISLYYELSENDLAFI-------KQCKEGSGFLINLIDSPGHVDFSSEVTAALRVTD 123

  Fly   128 GALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVI 192
            ||||||||||||||||||||||||||||||:|.|||||||||||||:.||||.||||||||||||
 Frog   124 GALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYLTFQRIVENVNVI 188

  Fly   193 IATYND-DGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMY-------SEKFKID------- 242
            |:||.: :.||||.:.:||..|:|||||||||||||||||:|||       .||.|::
 Frog   189 ISTYGEGESGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGEKTKLNPADRAKK 253

  Fly   243 VVKLMNRLWGENFFNAKTKKWQK-QKEADNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLE 303
            |..:|.:|||:.:|:..|.|:.| ...|:.|   |:|...|||||:|:||||||:||||...|:|
 Frog   254 VEDMMKKLWGDKYFDPSTGKFSKTATNAEGKKLPRTFSQLILDPIFKIFDAIMNFKKEETAKLIE 318

  Fly   304 KIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAA 368
            |:.:.|..|||:|:||.|||.|||.|||||:||||||.|||||||.|||||.|:|||||.|||||
 Frog   319 KLDIKLDTEDKEKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAA 383

  Fly   369 IAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAI 433
            :.||||||.|||:||||||||||||||||||||||:|.|:||||.||||||||||||||||.|.|
 Frog   384 LGVKSCDPKGPLVMYISKMVPTSDKGRFYAFGRVFSGIVSTGQKVRIMGPNYTPGKKEDLYLKPI 448

  Fly   434 QRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPK 498
            ||||||||||||.|||||.|||.||||||||||||||||||:.||||:|||||||||||||||.|
 Frog   449 QRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAK 513

  Fly   499 NPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVV 563
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   514 NPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVV 578

  Fly   564 SYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYD 628
            ||||||||||.|:||||||||||||.|||.|.||||.||||.||||::.|.|.|||||:|||::|
 Frog   579 SYRETVSEESSQLCLSKSPNKHNRLFMKARPFPDGLAEDIDKGDVSSRQELKQRARYLAEKYEWD 643

  Fly   629 VTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDV 693
            |.||||||||||||||||.::|.||.||||||||||||||||||:|||:|.:|||||.||:|:||
 Frog   644 VAEARKIWCFGPDGTGPNILVDVTKGVQYLNEIKDSVVAGFQWATKEGVLCEENLRGARFDIHDV 708

  Fly   694 TLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFE 758
            |||||||||||||||||.||.|||:|:||:||||||:||.||||||..||||||||||:||||||
 Frog   709 TLHADAIHRGGGQIIPTARRVLYASALTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFE 773

  Fly   759 ENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQD 823
            |:||.|||||||||||||||||||||||||||||||||||||||||:|||||.:.:|:|..:|.:
 Frog   774 ESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDSTSRPSQVVGE 838

  Fly   824 TRKRKGLKEGLPDLSQYLDKL 844
            ||||||||||:|.|..:||||
 Frog   839 TRKRKGLKEGIPPLDNFLDKL 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	679/864 (79%)
eef2.2	NP_001015785.1	PTZ00416	1..859	CDD:240409	679/864 (79%)