Protein Alignment eEF2 and mRRF2

DIOPT Version :9

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Alignment Length: 863
• Identity: 193/863 - (22%)
• Similarity: 327/863 - (37%)
• Gaps: 270/863 - (31%)

  Fly    19 IRNMSVIAHVDHGKSTLTDSLVSKAG---IIAGAKAGETRFTDTRKDEQERCITIKSTAISMYFE 80
            |||:.::||:|.||:|.|:.::..||   .:.....|.| .||....|:||.|||.|:|::..:.
  Fly    33 IRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNT-VTDYLTQERERGITICSSAVTFSWN 96

  Fly    81 VEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 145
                        |.|        |||:|:|||:||:.||..:|...||.:||:|..:||..||.|
  Fly    97 ------------DHR--------INLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVT 141

  Fly   146 VLRQAIAERIKPILFMNKMDRALLELQ---LDAEELYQT----FQRIVENVNVIIA--------- 194
            |..||...::..::|:|||||...:.:   .|.::..:|    .|..|:|.:.::|
  Fly   142 VWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAINDVITLER 206

  Fly   195 ---TYNDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKIDVVKLMNRLWG---- 252
               ...|.|.....|:::||.              .|:...|..:|        |:::|.|
  Fly   207 LSWQQKDLGRSYRNVKLEPSD--------------DLRLLQEKRNE--------LIDQLSGLDDE 249

  Fly   253 --------ENFFNAKTKKWQKQ-KEADNKRSFCMYILDPIYK------VFDAIMNY-----KKEE 297
                    |:|.|......::. :.|..::.....:|...||      :.||:..|     ::.:
  Fly   250 LADVVISTESFDNVDNALIERALRRATTQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQ 314

  Fly   298 I----GTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEML 358
            |    ||  |..|...|.....:.|...|..::|..:..|   :::|:....:.||::      |
  Fly   315 IYDCFGT--EVAGKVFKIVHDKQRGPLTLVRILRGEIKRG---MRLISARGQAEVVSK------L 368

  Fly   359 YEGPHDDEAAI-AVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTP 422
            ||...|:...: ||:|.|.                             .:..|.|..:.|...|.
  Fly   369 YEPLADEYREVSAVQSGDV-----------------------------VICAGLKSTVTGDLLTS 404

  Fly   423 GKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSV 487
            .      :.|::..   ..||.:::     ||....|..|..|.::..:             |::
  Fly   405 S------QSALKNA---QKRYKQSL-----GNTAAKVEEDDELDESDEL-------------FAI 442

  Fly   488 SPVVRVAV-----EPKNPADLPKLVEGLKRLAKSDPMVQCIIEE-SGEHIIAGAGELHLEI---- 542
            .|.:..||     ||.:.:....:.:.||:|.:.||.::...:. :|:.::.|.||||::|
  Fly   443 DPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSR 507

  Fly   543 CLKDLEEDHACIPLKKSDPVVSYRETV----------------SEESDQMCLSKSPNKHNRLLMK 591
            .|.:.:.|....||:     ::|:||:                |::|..:.|....|:..  |..
  Fly   508 ILSEYKIDVDLGPLQ-----IAYKETIEAPALTTLSVEKEIAGSKQSVSITLEVVKNQAE--LFS 565

  Fly   592 ALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQ 656
            ....||.||.
  Fly   566 LDKSPDNLPN------------------------------------------------------- 575

  Fly   657 YLNEIKDSVVAGFQWASKEGILADENLRGVRFN----IYDVTLHADAIHRGGGQ--IIPTTRRCL 715
             ||.::..::   |...|..|.|.|  ||.|..    ...:.||...|.||...  ::.|..:|:
  Fly   576 -LNTLRPRIL---QVLRKGSISALE--RGPRVGGQVVETQIRLHNATIGRGTADSFVMATAAQCV 634

  Fly   716 YAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVV----GTPMFVVKAYLPV 776
            .....|:..||:||:...:|..|...:.||...|:|||..:   |.|:    ...|.:|.|  |:
  Fly   635 QKLLSTSGTRLLEPIMALQIVAPSERISGIMADLSRRRALI---NDVLPKGERNKMILVNA--PL 694

  Fly   777 NESFGFTADLRSNTGGQA 794
            .|..|:::.||:.:.|.|
  Fly   695 AELSGYSSALRTISSGTA 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	193/863 (22%)
		EF2	20..236	CDD:206672	69/237 (29%)
		EF2_snRNP_like_II	380..474	CDD:293901	12/93 (13%)
		EF2_snRNP_III	489..560	CDD:293918	21/80 (26%)
		aeEF2_snRNP_like_IV	560..732	CDD:238839	34/193 (18%)
		eEF2_snRNP_like_C	728..807	CDD:239763	22/71 (31%)
mRRF2	NP_732771.2	PRK12739	31..733	CDD:237185	193/863 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840