Protein Alignment eEF2 and mEFG1

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Alignment Length: 849
• Identity: 208/849 - (24%)
• Similarity: 336/849 - (39%)
• Gaps: 182/849 - (21%)

  Fly    19 IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGA-------KAGETRFTDTRKDEQERCITIKSTAIS 76
            |||:.:.||:|.||:|||:.::...|.||..       ..|.|  .|:.:.|::|.|||:|.|..
  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGAT--MDSMELERQRGITIQSAATY 104

  Fly    77 MYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCV 141
            ..:                    |...||:||:||||||:.||..||||.|||::|:..|.||..
  Fly   105 TLW--------------------KDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQS 149

  Fly   142 QTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYNDDGGPMGEV 206
            ||.||.||.....:..:.|:||:||.       ....|:...::...:|...|......|.....
  Fly   150 QTLTVNRQMKRYNVPCLAFINKLDRL-------GSNPYRVLSQMRSKMNHNAAFIQLPIGVESNC 207

  Fly   207 R--VDPSKGSVGFGSGLHGWAFTLKQF-SEMYSEKFK-----IDVVKLMNRLWGENFFNAKTKKW 263
            :  ||..:....:..|.||....|.:. .:|..|..:     |:.:...:...||.|...|....
  Fly   208 KGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTE 272

  Fly   264 QKQKEADNKRSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRT 328
            ...|.|  .|..|      |.:.|..::      :||.|:..||
  Fly   273 DDIKAA--LRRTC------INRTFTPVL------VGTALKNKGV--------------------- 302

  Fly   329 WLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDPDGPLMMYISKMVPTSDK 393
                 :.||..:..:||:|  .:...:..:.:...|.|..:...:.|...|.:....|:    :.
  Fly   303 -----QPLLDAVLDYLPNP--GEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFKL----EA 356

  Fly   394 GRF--YAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTILMMGRYVEAIEDVPSGNIC 456
            |||  ..:.|.:.|.:..|....    |....||     ..|.|.:.:....:|.:.:|.:|:|.
  Fly   357 GRFGQLTYLRCYQGVLRKGDNIF----NARTNKK-----VRIARLVRLHSNQMEDVNEVYAGDIF 412

  Fly   457 GLVGVDQFLVKTGTITTFKDAHNMKVMK-FSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMV 520
            .|.|||   ..:|...|....:|:.:.. |...|||.:|::|.|..|.....:.:.|..|.||..
  Fly   413 ALFGVD---CASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTF 474

  Fly   521 QCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESDQMCLSKSPNK 584
            ....: :..|.:::|.|||||||..:.:|.::.| |:....|.|::|||:..
  Fly   475 HFFFDNDVKETLVSGMGELHLEIYAQRMEREYGC-PVTLGKPKVAFRETLVG------------- 525

  Fly   585 HNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTE-ARKIWCFGPDGTGPNFI 648
                           |.:.|               ||.:|......: ||.|....|.....|.:
  Fly   526 ---------------PCEFD---------------YLHKKQSGGSGQYARIIGVMEPLPPNQNTL 560

  Fly   649 L---DCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPT 710
            |   |.|.......:....|..|::..:::|:|:...|.|:||.:.|          ||..|:.:
  Fly   561 LEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQD----------GGHHIVDS 615

  Fly   711 TRRCLYAAAITA--------KPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPM 767
            :......||..|        ..:::||:.|.|:..||...|.:.|.|::|.|.:.......|  .
  Fly   616 SELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEG--W 678

  Fly   768 FVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKE 832
            |.|.|.:|:|:.||:..:|||:|.|:.  :...::.:..|..|.....    ||:..::.:||.:
  Fly   679 FTVYAEVPLNDMFGYAGELRSSTQGKG--EFTMEYSRYSPCLPDVQDQ----IVRQYQESQGLAQ 737

  Fly   833 GLPD 836
              ||
  Fly   738 --PD 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	208/849 (24%)
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	204/837 (24%)