Protein Alignment eEF2 and eef2b

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_956752.2
• Gene: eef2b / 326929
• ZFINID: ZDB-GENE-030131-5128
• Length: 858
• Species: Danio rerio
• Alignment Length: 867
• Identity: 684/867 - (78%)
• Similarity: 746/867 - (86%)
• Gaps: 32/867 - (3%)

  Fly     1 MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQE 65
            |||||||:||.:||||.||||||||||||||||||||||||||||||.|:|||||||||||||||
Zfish     1 MVNFTVDQIRAIMDKKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQE 65

  Fly    66 RCITIKSTAISMYFEVEEKDLVFITHPDQREKECK---GFLINLIDSPGHVDFSSEVTAALRVTD 127
            |||||||||||||:|:.|.||.||       |:||   |||||||||||||||||||||||||||
Zfish    66 RCITIKSTAISMYYELTENDLAFI-------KQCKDGSGFLINLIDSPGHVDFSSEVTAALRVTD 123

  Fly   128 GALVVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVI 192
            ||||||||||||||||||||||||||||||:|.|||||||||||||:.|||||||||||||||||
Zfish   124 GALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVI 188

  Fly   193 IATY-NDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKF---------------KI 241
            |:|| .|:|||||.:.:||..|:|||||||||||||||||:|||..||               |:
Zfish   189 ISTYGEDEGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGEAQLSPADRCKKV 253

  Fly   242 DVVKLMNRLWGENFFNAKTKKWQKQKEA-DNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLL 302
            :  .:|.:|||:.:|:....|:.|.... |.|   |:|...|||||:||||||||:||||...|:
Zfish   254 E--DMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFKKEETAKLI 316

  Fly   303 EKIGVTLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEA 367
            ||:.:.|..|||||:||.|||.|||.||||||||||||.|||||||.|||||.|:|||||.||||
Zfish   317 EKLDIKLDTEDKDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPGDDEA 381

  Fly   368 AIAVKSCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKA 432
            |:.:|:|||.|||||||||||||:||||||||||||:|.|:||.|.||||||||||||||||.|.
Zfish   382 AMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKP 446

  Fly   433 IQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEP 497
            |||||||||||||.|||||.|||.||||||||||||||||||..||||:|||||||||||||||.
Zfish   447 IQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFDQAHNMRVMKFSVSPVVRVAVEA 511

  Fly   498 KNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPV 562
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   512 KNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPV 576

  Fly   563 VSYRETVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDY 627
            ||||||||.|||||||||||||||||.|||.|.||||.||||.||||::.|.|.|||||::||::
Zfish   577 VSYRETVSAESDQMCLSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSRQELKTRARYLADKYEW 641

  Fly   628 DVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYD 692
            :||||||||||||||||||.::|.||.||||||||||||||||||:|||.|.:||:|.|||:|:|
Zfish   642 EVTEARKIWCFGPDGTGPNMLVDVTKGVQYLNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHD 706

  Fly   693 VTLHADAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVF 757
            ||||.|||||||||||||.||.|||..:||:||||||:||.||||||..||||||||||:|||||
Zfish   707 VTLHTDAIHRGGGQIIPTARRVLYACQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVF 771

  Fly   758 EENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQ 822
            ||:||:|||||||||||||||||||||||||||||||||||||||||:|||||.:.:|||..||.
Zfish   772 EESQVMGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPKDAASKPCQIVA 836

  Fly   823 DTRKRKGLKEGLPDLSQYLDKL 844
            |||||||||||:|.|..:||||
Zfish   837 DTRKRKGLKEGIPALDNFLDKL 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	682/865 (79%)
eef2b	NP_956752.2	PTZ00416	1..858	CDD:240409	682/865 (79%)