Protein Alignment eEF2 and Eef2

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_058941.1
• Gene: Eef2 / 29565
• RGDID: 61979
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 862
• Identity: 677/862 - (78%)
• Similarity: 747/862 - (86%)
• Gaps: 22/862 - (2%)

  Fly     1 MVNFTVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQE 65
            |||||||:||.:||||.|||||||||||||||||||||||.||||||.|:|||||||||||||||
  Rat     1 MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQE 65

  Fly    66 RCITIKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGAL 130
            |||||||||||:::|:.|.||.||    ::.|:..||||||||||||||||||||||||||||||
  Rat    66 RCITIKSTAISLFYELSENDLNFI----KQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGAL 126

  Fly   131 VVVDCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIAT 195
            |||||||||||||||||||||||||||:|.|||||||||||||:.||||||||||||||||||:|
  Rat   127 VVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIIST 191

  Fly   196 YND-DGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKI-------------DVVKL 246
            |.: :.||||.:.:||..|:|||||||||||||||||:|||..||..             .|..:
  Rat   192 YGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGAAERAKKVEDM 256

  Fly   247 MNRLWGENFFNAKTKKWQKQKEA-DNK---RSFCMYILDPIYKVFDAIMNYKKEEIGTLLEKIGV 307
            |.:|||:.:|:....|:.|...: |.|   |:||..|||||:||||||||::|||...|:||:.:
  Rat   257 MKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFRKEETAKLIEKLDI 321

  Fly   308 TLKHEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVK 372
            .|..|||||:||.|||.|||.|||||:||||||.|||||||.|||||.|:|||||.|||||:.:|
  Rat   322 KLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIK 386

  Fly   373 SCDPDGPLMMYISKMVPTSDKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRTI 437
            ||||.||||||||||||||||||||||||||:|.|:||.|.||||||||||||||||.|.|||||
  Rat   387 SCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTI 451

  Fly   438 LMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPAD 502
            ||||||||.|||||.|||.||||||||||||||||||:.||||:|||||||||||||||.|||||
  Rat   452 LMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPAD 516

  Fly   503 LPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRE 567
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
  Rat   517 LPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRE 581

  Fly   568 TVSEESDQMCLSKSPNKHNRLLMKALPMPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEA 632
            ||||||:.:||||||||||||.|||.|.||||.||||.|:|||:.|.|||||||:|||::||.||
  Rat   582 TVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKARARYLAEKYEWDVAEA 646

  Fly   633 RKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHA 697
            ||||||||||||||.:.|.||.||||||||||||||||||:|||.|.:||:|||||:::||||||
  Rat   647 RKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHA 711

  Fly   698 DAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQV 762
            |||||||||||||.||||||:.:||:||||||:||.||||||..||||||||||:|||||||:||
  Rat   712 DAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQV 776

  Fly   763 VGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKR 827
            .|||||||||||||||||||||||||||||||||||||||||:|||||.:.||:|..:|.:||||
  Rat   777 AGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKR 841

  Fly   828 KGLKEGLPDLSQYLDKL 844
            ||||||:|.|..:||||
  Rat   842 KGLKEGIPALDNFLDKL 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	675/860 (78%)
Eef2	NP_058941.1	PTZ00416	1..858	CDD:240409	675/860 (78%)