Protein Alignment eEF2 and ria1

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_587766.1
• Gene: ria1 / 2539293
• PomBaseID: SPCC553.08C
• Length: 1000
• Species: Schizosaccharomyces pombe
• Alignment Length: 996
• Identity: 323/996 - (32%)
• Similarity: 500/996 - (50%)
• Gaps: 192/996 - (19%)

  Fly     7 DEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIK 71
            :::..|...:.||||.:::|||||||:||.|||::..|||:...||..||.|.|:||..|.||:|
pombe     7 EKLVSLQKNQENIRNFTLLAHVDHGKTTLADSLLASNGIISSKLAGTVRFLDFREDEITRGITMK 71

  Fly    72 STAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCV 136
            |:|||::|:|       |:..|::..| |.:|||||||||||||||||::|.|:.|||.|:||.|
pombe    72 SSAISLFFKV-------ISQNDEKRVE-KDYLINLIDSPGHVDFSSEVSSASRLCDGAFVLVDAV 128

  Fly   137 SGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATY----- 196
            .|||.||.||||||..:|||.||.:|||||.:.||:|...|.:....|:||.||.:|.|:
pombe   129 EGVCSQTITVLRQAWIDRIKVILVINKMDRLITELKLSPIEAHYHLLRLVEQVNAVIGTFYTGEL 193

  Fly   197 ----------NDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKIDVVKLMNRLW 251
                      :|:|     :...|.:|:|.|.|...||||.|.||||.|.:|..:....|...||
pombe   194 MQLADNDEVISDEG-----IYFAPEQGNVVFASAYDGWAFCLDQFSEFYEKKLGLKQKALTKCLW 253

  Fly   252 GENFFNAKTKKWQKQKEADNKR---SFCMYILDPIYKVFD-AIMNYKKEEIGTLLEKIGV-TLKH 311
            |:.:.:.|||:..:.|....:|   .|..::|:.::.|:: |:.|...|.|..:::.:.: .|..
pombe   254 GDYYLDPKTKRVLQPKHLQGRRLKPMFVQFVLENLWAVYESAVSNRNLENIEKIIKALNIKVLPR 318

  Fly   312 EDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYR-MEMLYEGPH----DDEAAIAV 371
            :.|.||.:.||..:.:.|||...|:|......:|||:.||..| .::|...||    |.:..:|:
pombe   319 DIKSKDPRNLLLAIFQQWLPLSTAILLTAIREIPSPINAQANRARKVLSSTPHYEMIDPDITLAM 383

  Fly   372 KSCD--PDGPLMMYISKMVPTS------------------------------------------- 391
            :|||  .:.|:::||||||..|
pombe   384 ESCDASKEQPVLVYISKMVAFSERDLPNHRRKQLSAEEMKLIRSKLSESIESGINTISIEENVSS 448

  Fly   392 ---------------DKGRFYAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEK-AIQRTILMM 440
                           ||.....|.|:::|.::.||:..:.||.|.|...|....| .::...|||
pombe   449 TNSDNLEGSTTDMDDDKDILIGFARIYSGTISVGQEVYVYGPKYDPVNPEKHITKVTVESLYLMM 513

  Fly   441 GRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPK 505
            |:.:..:|.||:||:..:.|:...:::|.|:.:..:..|:..:...:.|:||||:||..|.::.|
pombe   514 GQELVYLETVPAGNVFAIGGLAGTVLRTATLCSSPNGPNLVGVTQQMEPIVRVALEPVRPFEMNK 578

  Fly   506 LVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVS 570
            ||.||..|.::||.||..:||:|||:|..|||:|||.|||||.|..|.|.::.|.|:|.||||..
pombe   579 LVTGLDMLNQADPCVQIAVEENGEHVIMCAGEIHLERCLKDLRERFAKIEIQASQPLVPYRETTI 643

  Fly   571 EESDQMCLSKSPN-------------------------------KHNRLL----------MKALP 594
            ...|.:..:|..:                               ||::.:          .:.:.
pombe   644 ATPDLLAKNKELSIGFVTATLPVGGVTIGITVTPLSGSVVDFLLKHSKTIENVSSNFSKKNRNVV 708

  Fly   595 MPDGLPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEAR----KIWCFGPDGTGPNFILDCTKSV 655
            :.:.|.:.::  :|...::|..|...|.|:.:.|:.|.:    .|..|||...|||.:.|.||.:
pombe   709 VSESLTKSME--EVLTPEKFYERLSKLLEEENSDLGELKNHLDSIIAFGPKRVGPNILFDKTKKM 771

  Fly   656 QYL-----------NEIKDSVVAGFQWASKEGILADENLRGV-----RFNIYD-------VTLHA 697
            :..           :::.:.||..||..:.:|.|..|.::|:     :|:|.|       :|::.
pombe   772 RDFRRQSDETKLIPSDLSEYVVTAFQLITHQGPLCAEPVQGICVSIDQFDISDDSEDSKLLTINN 836

  Fly   698 DAIHRGGGQIIPTTRRCLYAAAITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQV 762
            ..|   .||:|...:..:....:...||||..:|.|::|.....:|.:|||:::|||.|.:|...
pombe   837 PQI---PGQVISVVKESIRHGFLGWSPRLMLAMYSCDVQATSEVLGRVYGVVSKRRGRVIDEEMK 898

  Fly   763 VGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDP----------------- 810
            .|||.|:|||.:||.|||||..::...|.|.|:||.:|..:::|..:|
pombe   899 EGTPFFIVKALIPVVESFGFAVEILKRTSGAAYPQLIFHGFEMLDENPFWVPTTEEELEDLGELA 963

  Fly   811 -SEPSSKPYAIVQDTRKRKGL 830
             .|..:|.|.:  :.||||||
pombe   964 DRENIAKRYML--NVRKRKGL 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	323/996 (32%)
ria1	NP_587766.1	PRK13351	1..985	CDD:481252	323/996 (32%)