Protein Alignment eEF2 and mEFG1

DIOPT Version :10

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_318822.5
• Gene: mEFG1 / 1279146
• VectorBaseID: AGAMI1_000113
• Length: 744
• Species: Anopheles gambiae
• Alignment Length: 871
• Identity: 204/871 - (23%)
• Similarity: 340/871 - (39%)
• Gaps: 230/871 - (26%)

  Fly    19 IRNMSVIAHVDHGKSTLTDSLVSKAGII-------AGAKAGETRFTDTRKDEQERCITIKSTAIS 76
            |||:.:.||:|.||:|||:.::...|.|       .....|.|  .|:.:.|::|.|||:|.|..
Mosquito    41 IRNIGISAHIDSGKTTLTERILFYTGRIKEMHEVKGKDNVGAT--MDSMELERQRGITIQSAATY 103

  Fly    77 MYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCV 141
            ..:                    |...||:||:||||||:.||..||||.|||::|:..|.||..
Mosquito   104 TIW--------------------KDHNINIIDTPGHVDFTVEVERALRVLDGAVLVLCSVGGVQS 148

  Fly   142 QTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIATYNDDGGPMGEV 206
            ||.||.||.....:..:.|:||:||:       ....|:.                     :|::
Mosquito   149 QTLTVNRQMKRYNVPCLAFINKLDRS-------GANPYRV---------------------LGQM 185

  Fly   207 RVDPSKGS------VGFGSGLHGWAFTLKQ----FSEMYSEKFKIDVVKLMNRLWGENFFNAKTK 261
            |...:..:      :|..|...|....:||    |.|.|..|.:.|.:..          :.:|:
Mosquito   186 RSKLNHNAAFVQLPIGVESNCKGVIDLVKQRALYFEEPYGLKIREDEIPA----------DMRTE 240

  Fly   262 KWQKQKEADNKRSFCMYILDPIYKVFDAIMNYKKEEIGTL-LEKIGVTLKHEDKDKDGKALLKTV 325
            ..::::|          :::.:..|        .|:||.| ||:...|:    .|..|.....|:
Mosquito   241 SAERRQE----------LIEHLSNV--------DEKIGELFLEEREATV----DDIMGAIRRSTL 283

  Fly   326 MRTWLP--AGEA--------LLQMIAIHLPSPVVAQKYRMEMLYEGPHDDEAAIAVKSCDP---- 376
            .|.:.|  .|.|        ||..:..:||.|             |..::.|.:..|..:|
Mosquito   284 KRAFTPVLVGTALKNKGVQPLLDAVLDYLPHP-------------GEVENVALVEKKDEEPQKVP 335

  Fly   377 -----DG--PLMMYISKMVPTSDKGRF--YAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKA 432
                 ||  |.:....|:    :.|||  ..:.|.:.|.:..|....    |...|||..|
Mosquito   336 LNPARDGKDPFVGLAFKL----EAGRFGQLTYLRCYQGVLRKGDNIF----NTRSGKKIRL---- 388

  Fly   433 IQRTILMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSV---SPVVRVA 494
             .|.:.:....:|.:.:|.:|:|..|.|||     ..:..||.....:::...|:   .|||.:|
Mosquito   389 -ARLVRLHSNQMEDVNEVYAGDIFALFGVD-----CASGDTFVTNPKLELSMESIFVPDPVVSMA 447

  Fly   495 VEPKNPADLPKLVEGLKRLAKSDPMVQCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPLKK 558
            ::|.|..|.....:.:.|..|.||......: :..|.:::|.|||||||..:.:|.::.| |:..
Mosquito   448 IKPTNSKDRDNFAKAIARFTKEDPTFHFEYDADVKETLVSGMGELHLEIYAQRMEREYNC-PVTL 511

  Fly   559 SDPVVSYRETVSE--ESDQMCLSKSPNKHNRLLMKAL--PMPDGLPEDIDNGDVSAKDEFKARAR 619
            ..|.|::|||:..  |.|.:...:|..:.....:..:  |:|   |.  .|..:...||
Mosquito   512 GKPKVAFRETLIGPCEFDYLHKKQSGGQGQYARVSGILEPLP---PH--QNTTIEFVDE------ 565

  Fly   620 YLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYLNEIKDSVVAGFQWASKEGILADENLR 684
                                            |.......:....:..||:..:::|:|:...|.
Mosquito   566 --------------------------------TMGTNVPKQFIPGIEKGFRQMAEKGLLSGHKLS 598

  Fly   685 GVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAAAITA--------KPRLMEPVYLCEIQCPEVA 741
            |::|.:.|          |...|:.::......||..|        ..:::||:.:.|:..||..
Mosquito   599 GIKFRLQD----------GAHHIVDSSELAFMLAAQGAIKSVFENGSWQILEPIMMVEVTAPEEF 653

  Fly   742 VGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVL 806
            .|.:.|.||:|.|.:.......|  .|.|.|.:|:|:.||:..:|||:|.|:......:..:...
Mosquito   654 QGTVIGQLNKRHGIITGTEGAEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFSMEYSRYSPC 716

  Fly   807 PGDPSEPSSKPYAIVQ----DTRKRK 828
            ..:..|.....|.:.|    |.:::|
Mosquito   717 MPEVQEKLCHEYQVSQGLVVDKKQKK 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	204/871 (23%)
mEFG1	XP_318822.5	None