Protein Alignment eEF2 and efl1

DIOPT Version :9

• Sequence 1: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_002940146.3
• Gene: efl1 / 100492738
• XenbaseID: XB-GENE-5894854
• Length: 1136
• Species: Xenopus tropicalis
• Alignment Length: 1137
• Identity: 338/1137 - (29%)
• Similarity: 518/1137 - (45%)
• Gaps: 336/1137 - (29%)

  Fly     5 TVDEIRGLMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCIT 69
            ::::|..|..:..||||:.::|||||||:||.|.|:|..|||:...||:.|:.|:|:|||.|.||
 Frog     5 SLEKIVTLQKRAANIRNICILAHVDHGKTTLADCLISSNGIISNRLAGKLRYLDSREDEQIRGIT 69

  Fly    70 IKSTAISMYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVD 134
            :||:|||::::.:|::                :|||||||||||||||||:.|:|:.||.::|||
 Frog    70 MKSSAISLHYKDDEEE----------------YLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVD 118

  Fly   135 CVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVI------- 192
            .|.|||.||:.|||||..|.|:|:|.:||:||.:.||:|...|.|...|:|:|.||.:
 Frog   119 SVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLITELKLSCLEAYSHLQKILEQVNAVTGSLFTS 183

  Fly   193 --------------IATYNDDGGPM------------GEVRVDPSKGSVGFGSGLHGWAFTLKQF 231
                          :.:...||..:            ..:...|.:|:|.|.|.:.||.||:..|
 Frog   184 KVLEERAEKDMASDVPSETVDGDQVYDWSAGLEETDDSHLYFSPDQGNVVFASAIDGWGFTIDHF 248

  Fly   232 SEMYSEKFKIDVVKLMNRLWGENFFNAKTKKWQKQKEADNKRS-FCMYILDPIYKVFDAIMNYKK 295
            :::||:|..|....|:..|||:.:.|.|.||..|..::..|:. |...|||.::.::||::..:|
 Frog   249 AQLYSQKVGIKAAVLLKTLWGDYYLNTKAKKIMKGAQSKGKKPLFVQLILDNLWSLYDAVIKREK 313

  Fly   296 EEIGTLLEKIGVTLK-HEDKDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSPVVAQKYRMEML- 358
            |:|..::..:|:.:. .|.:..|.|..:..:...|||..:|:|.|:...||||:.....|:|.|
 Frog   314 EKIDKIVLSLGLKISPRESRHSDPKVHVNAICSQWLPISQAVLSMVCRKLPSPLDIPAERVEKLL 378

  Fly   359 -----------YEGPHDDEAAIAVKSCDPDGPLMMYISKM------------------------- 387
                       .|.....|..:..:| |...|:::::|||
 Frog   379 CVGSRRFDSLPQETQQLKETFLKCRS-DETAPVIIFVSKMFAVDAKALPQNKQRPLTQEEIALRR 442

  Fly   388 ----------------------VPTS----------------------------------DKGRF 396
                                  ||:|                                  :|..|
 Frog   443 ELARQRHAEKMAINQEQLPAEQVPSSNECEMPANKENTKGDKQTSHRDPEVVKPEKQEAENKSYF 507

  Fly   397 YAFGRVFAGKVATGQKCRIMGPNYTPGKKEDLYEKAIQRT-------------------ILMMGR 442
            .||.|||:|.|..|||..::||.|.|.  |.|.:..:..|                   .|:|||
 Frog   508 IAFARVFSGIVRRGQKIFVLGPKYDPA--ETLLKLPLNCTPACDLPGIPHMACCSLDNLYLLMGR 570

  Fly   443 YVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVMKFSVSPVVRVAVEPKNPADLPKLV 507
            .:|.:|:||.||:.|:.|:::|::|:.|::|.........:.|..:|:||||||||:|:::|:||
 Frog   571 ELENLEEVPVGNVLGIGGLEEFVLKSATLSTSPACPPFIPLNFEATPIVRVAVEPKHPSEMPQLV 635

  Fly   508 EGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRET---- 568
            :|:|.|.::||.|:.:|:|:|||::..|||:||:.||.||.|..|.|.:..|.|::.:|||
 Frog   636 KGMKLLNQADPCVEVLIQETGEHVLITAGEVHLQRCLDDLRERFAKIQVSSSAPIIPFRETIIRP 700

  Fly   569 -----VSEE---------------------------SDQMCLSKSPNKHNRLLMKALPMPDGLPE 601
                 |:||                           .|.:....:|||...|.::|:|:|:.:.:
 Frog   701 PKVDMVNEEIGKQQKIAVIHQVKEEQSKCPEGVQVDPDGLVTLTTPNKLATLSVRAMPLPEEVTQ 765

  Fly   602 DID-NGDVSAKDE-------------------------FKARARYLSEKYDYDVTEARKIWCFGP 640
            .:: |.|:....|                         ||:..:.|.:...:. ....:||.|||
 Frog   766 LLEKNSDLIRTMEQINMALNEGSYTIHFNESAIERITAFKSNLQQLLQGRRWR-NAVDQIWSFGP 829

  Fly   641 DGTGPNFILD------------C-TKSV---QYLNEIKDSVVAGFQWASKEGILADENLRGVRFN 689
            ...|||.:|:            | .||:   :|.| ..:|:|:|||.|:..|.:.:|.|.||.|.
 Frog   830 RRYGPNILLNRIEGYDRPSVWQCLEKSIREGKYRN-FDNSIVSGFQLATLAGPMCEEPLMGVCFI 893

  Fly   690 IYDVTL-----------------------HADAIHRG---------------------------- 703
            :..:.|                       |::....|
 Frog   894 VEKLDLSRPLLAKDSASQDSEVDTRTEPEHSETGTTGTTGALINNISTSATEETELIPENGARPF 958

  Fly   704 ---------------GGQIIPTTRR-CLYAAAITAKP-RLMEPVYLCEIQCPEVAVGGIYGVLNR 751
                           .||:|.|.:. |.||..:  || |||..:|.|||......:|.:||||::
 Frog   959 SKRKGDLLTDCYGPFSGQLIATMKEACRYAFQV--KPQRLMAAMYTCEIMATAEVLGRVYGVLSK 1021

  Fly   752 RRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDP------ 810
            |.|.|..|....||.||::||.|||.|||||..::|..|.|.|.||.||.||:|:..||
 Frog  1022 REGRVLLEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVISSDPFWVPTT 1086

  Fly   811 ------------SEPSSKPYAIVQDTRKRKGL 830
                        ||..::.|  :...||||||
 Frog  1087 EEEYLHFGEKADSENQARKY--MNSVRKRKGL 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	338/1137 (30%)
		EF2	20..236	CDD:206672	99/248 (40%)
		EF2_snRNP_like_II	380..474	CDD:293901	40/193 (21%)
		EF2_snRNP_III	489..560	CDD:293918	36/70 (51%)
		aeEF2_snRNP_like_IV	560..732	CDD:238839	62/317 (20%)
		eEF2_snRNP_like_C	728..807	CDD:239763	38/78 (49%)
efl1	XP_002940146.3	FusA	5..1119	CDD:357662	338/1137 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920