DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul2 and AT1G59800

DIOPT Version :9

Sequence 1:	NP_610117.1	Gene:	Cul2 / 35420	FlyBaseID:	FBgn0032956	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_176189.1	Gene:	AT1G59800 / 842273	AraportID:	AT1G59800	Length:	255	Species:	Arabidopsis thaliana

Alignment Length:	284	Identity:	59/284 - (20%)
Similarity:	114/284 - (40%)	Gaps:	57/284 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PKIVEFVDVWPRLRCIAESVITLTKVE------RSVWNTSFSDVYTLCVAQPEPMADRLYGETKH 63
            |..::|...|..::.....:|.:.:.|      :.:.....:..|.:| |...|  .:||.:.:.
plant     4 PTEIKFEVEWSNIQQGFTKLIRMIEGESEPAFNQEIMMMMHTATYRIC-AYKNP--QQLYDKYRE 65

  Fly    64 FLEQH-VQEMLAKKVLIEGECSHSNGGPDLLQRYYITWMEYSQGIKYLHQLYIYLNQQHIKKQKI 127
            .:|.: :|.:|........||        :|:.....|..:...::...:..:||:...:.|:.:
plant    66 LIENYAIQTVLPSLREKHDEC--------MLRELAKRWNAHKLLVRLFSRRLVYLDDSFLSKKGL 122

  Fly   128 TDTESFYGNLSSDAAEQMEIGELGLDIWRLYMIEYLSSELVRHIL-------EGIAADRASNGTL 185
            .                 .:.|:||:.:|..:...:.|.....||       ||...||
plant   123 P-----------------SLREVGLNCFRDQVYREMQSMAAEAILALIHKEREGEQIDR------ 164

  Fly   186 DHHRVQIINGVIHSFVEVQDYKKTGSLKLYQELFEGPMLEASGAYYTDEANKLLHRCSVSEYMQE 250
                 :::..||..|||    ...|:||.|:|.||..||:.:.:||:.:|::.:...|..:|..:
plant   165 -----ELVRNVIDVFVE----NGMGTLKKYEEDFERLMLQDTASYYSSKASRWIQEESCLDYTLK 220

  Fly   251 VIRILEYESRRAQKFLHVSSLPKL 274
            ..:.|:.|..|...:||.::.|||
plant   221 PQQCLQRERERVTHYLHPTTEPKL 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul2	NP_610117.1	Cullin	39..639	CDD:279260	54/244 (22%)
		CULLIN	436..575	CDD:214545
		Cullin_Nedd8	680..745	CDD:214883
AT1G59800	NP_176189.1	Cullin	41..>255	CDD:279260	54/247 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820