DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul2 and AT4G12100

DIOPT Version :9

Sequence 1:	NP_610117.1	Gene:	Cul2 / 35420	FlyBaseID:	FBgn0032956	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_192947.1	Gene:	AT4G12100 / 826818	AraportID:	AT4G12100	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	370	Identity:	78/370 - (21%)
Similarity:	143/370 - (38%)	Gaps:	89/370 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 WNTSFSDVYTLCVAQPEPMADRLYGETKHFLEQHVQEMLAKKVLIEGECSHSNGGPDLLQRYYIT 99
            :.|.|..|...|:..|. .::.::...||..|.|:.|::..   :|..||.|:.....|...|..
plant   106 FTTIFRAVKRACLGDPR-QSELVFNLVKHECEPHIAELIQS---LEKNCSGSDDPSVFLPHVYNR 166

  Fly   100 WMEYSQGIKYLHQLYIYLNQQHIKKQKITDTESFYGNLSSDAAEQMEIGELGLDIW--------- 155
            |:::                    |:|:        :|.||.|....:.  ||.:|
plant   167 WLDF--------------------KRKM--------SLVSDVAMYQTLN--GLTLWDVGQKLFHK 201

  Fly   156 RLYMIEYLSSELVRHILEGIAADR---ASNGTLDHHRVQIINGVIHSFVEVQDYKKTGSLKLYQE 217
            :|.|...|..:::..||..|..:|   |:|.|.|     ::..::..|  ...::.|       .
plant   202 QLSMAPQLQDQVITGILRLITDERLGKAANNTSD-----LLKNLMDMF--RMQWQCT-------Y 252

  Fly   218 LFEGPMLEASGAYYTDEANKLLHRCSVSEYMQEVIRILEYESRRAQK--FLHVSSLPKLRKECEE 280
            :::.|.|:::..:|.:||.::|.|..:|.|::.|.|....|..:..|  |...||..:|.|..:.
plant   253 VYKDPFLDSTSKFYAEEAEQVLQRSDISHYLKYVERTFLAEEEKCDKHYFFFSSSRSRLMKVLKS 317

  Fly   281 KFINDRLGFIYSECREMVSEERRQDLRNMYVVLKPIPDNLKSELITTFLDHI-------KSEGLQ 338
            :.:.....|:......::.|....|||.||.:...:...       .::|.|       |.||.:
plant   318 QLLEAHSSFLEEGFMLLMDESLIDDLRRMYRLFSMVDSE-------DYIDRILRAYILAKGEGAR 375

  Fly   339 TVSALKGENIHIAFVENMLKVHHK-------YQELIADVFENDSL 376
            ...:|  :.:|    .::.|:.|:       ..:.|.|.||...|
plant   376 QEGSL--QELH----TSIDKIWHQCFGQDDLLDKTIRDCFEGFGL 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul2	NP_610117.1	Cullin	39..639	CDD:279260	77/366 (21%)
		CULLIN	436..575	CDD:214545
		Cullin_Nedd8	680..745	CDD:214883
AT4G12100	NP_192947.1	Cullin	82..>412	CDD:279260	77/366 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820