Protein Alignment Ac3 and Phlpp2

DIOPT Version :9

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_001102601.2
• Gene: Phlpp2 / 498949
• RGDID: 1562857
• Length: 1359
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 65/354 - (18%)
• Similarity: 114/354 - (32%)
• Gaps: 137/354 - (38%)

  Fly   696 TFVRTEHIVSESEFNVTASLESDINLVVEGMVTAEHLLPASFV---------------EQMRDAV 745
            |...|....|.|..:.::|..||::||   :.|.|  .|||.:               :.:|...
  Rat    75 TTTATTTTTSSSSSSSSSSSSSDLHLV---LCTVE--TPASEICAGEGRESLYLQLHGDLVRRLE 134

  Fly   746 PTER---VLYPSYLSNFGVLILIAIAVIAQLTHLTKILLLLSIAALHCYFNIFIMQDLYALEDDF 807
            ||||   ::| .|||..|                                    .:|...::::.
  Rat   135 PTERPLQIVY-DYLSRLG------------------------------------FEDPVRIQEEA 162

  Fly   808 EHQPIISTRYAASGLLLVAALALSTLAR-------HMDHEDRVIFKWKTEVAEQKETANDMRQRN 865
            .:..                  ||.:.|       .|||.||::......|.:.|...:...:|.
  Rat   163 TNPD------------------LSCMIRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERL 209

  Fly   866 EALV----------------YNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFY 914
            ..|.                .::||: |.....:..:|.|...:|.:.|:......|....:::.
  Rat   210 VVLCGTCLIVSSVKDCQTGKMHILPL-VGGKIEEVKRRQHSLAFSSAGAQAQTYHVSFETLAEYQ 273

  Fly   915 SEETVNNQGLECLRFLNEVISDFD----ALLELPQF----QDIIKIKTIGSTYMAASGINVQRTV 971
            ..:.      :..:.:::.||..|    :|.|:|:.    |||        ||:         .:
  Rat   274 RWQR------QASKVVSQRISTVDLSCYSLEEVPEHLFYSQDI--------TYL---------NL 315

  Fly   972 RNDAPITERWSHLAILVEFA----LELKH 996
            |::....||...|..|.:|:    |.|.|
  Rat   316 RHNFMQLERPGGLDTLYKFSQLKGLNLSH 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831
		CYCc	256..453	CDD:214485
		Guanylate_cyc	294..476	CDD:278633
		CYCc	860..1071	CDD:214485	30/165 (18%)
		Guanylate_cyc	892..1092	CDD:278633	23/117 (20%)
Phlpp2	NP_001102601.2	RA_PHLPP2	66..178	CDD:340761	28/162 (17%)
		PH_PHLPP-like	185..279	CDD:270131	14/100 (14%)
		PLN00113	284..>762	CDD:215061	20/78 (26%)
		leucine-rich repeat	289..309	CDD:275380	4/19 (21%)
		leucine-rich repeat	310..336	CDD:275380	9/42 (21%)
		leucine-rich repeat	337..359	CDD:275380	3/8 (38%)
		leucine-rich repeat	360..382	CDD:275380
		leucine-rich repeat	383..405	CDD:275380
		leucine-rich repeat	406..428	CDD:275380
		leucine-rich repeat	429..452	CDD:275380
		leucine-rich repeat	453..476	CDD:275380
		leucine-rich repeat	477..497	CDD:275380
		leucine-rich repeat	498..517	CDD:275380
		leucine-rich repeat	518..539	CDD:275380
		leucine-rich repeat	540..562	CDD:275380
		leucine-rich repeat	563..584	CDD:275380
		leucine-rich repeat	586..607	CDD:275380
		leucine-rich repeat	608..631	CDD:275380
		leucine-rich repeat	632..681	CDD:275380
		leucine-rich repeat	682..705	CDD:275380
		leucine-rich repeat	706..728	CDD:275380
		leucine-rich repeat	751..772	CDD:275380
		PP2Cc	820..1069	CDD:238083

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900