Protein Alignment Ac3 and Gyc89Da

DIOPT Version :10

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_001036718.1
• Gene: Gyc89Da / 42001
• FlyBaseID: FBgn0038435
• Length: 667
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 150/705 - (21%)
• Similarity: 248/705 - (35%)
• Gaps: 245/705 - (34%)

  Fly   423 VELANKMESSGKAGRVHISDKTLA--------FLNGEFEVEAAFGEKREELLRIAGLK------- 472
            :|..|.: |.|.||.:.::|..|.        |.|.|:..:....|.....|::..:|
  Fly   165 IESQNDI-SGGTAGPIKLTDGPLTVIVKYRLDFDNREYMAKRVNTEAHPSQLKMPTVKLDVFLDL 228

  Fly   473 ---TYFITKVVKAFASPCAKKINETQAEIAHPNPNGS--------TTDIVSDEDDNDATLDDEEL 526
               |:.:...:|  .:...:||.||.  |.| ||..:        ..|:.......|.|:|.:.|
  Fly   229 FPFTFVLNHDMK--ITHAGEKIVETW--IMH-NPGANPKSFIGTHVMDLFQCRRPKDTTIDWDTL 288

  Fly   527 LAQNSVSNGHQIGIAVTADEEEQVKLENFKQRLKDELVTRDGHENLTKDTNIFLRFKNPQLEQLY 591
            :...:|                   |..|      ||: |.||.....|..:.:.|:|
  Fly   289 IQMRAV-------------------LFEF------ELI-RTGHNRAAYDAVLNMDFEN------- 320

  Fly   592 AVYREPYSSLPLLAALLVQCIDVLYSYLVLPRSTLHFINIAAPLVPIAMLVVISLAESFSGMLPK 656
                  |..:.|..                                 |..:.::.|:.||
  Fly   321 ------YDEMDLNE---------------------------------AQTMALAKAQEFS----- 341

  Fly   657 FFVDVSKRFNDITFVRELAAIIIALTIGFSNVIDMFFFVTFVRTEHIVSESEFNVTASLESDINL 721
                                                       ..|.|.:.|    ::.|.:|:
  Fly   342 -------------------------------------------ESHPVDDDE----SAREDEID- 358

  Fly   722 VVEGMVTAEHLLPASFVEQMRDAVPTERVLYPS---YLSNFGVLILIAIAVIAQLTHLTKILLLL 783
                        ||:  .:.|.:.....:|...   |:.:...||.:...:|..|..|..|.|.|
  Fly   359 ------------PAT--GERRSSQGLRSILLKGQMFYIKDVDSLIFLCSPLIENLDELHGIGLYL 409

  Fly   784 SIAALHCYFNIFIM---QDLYALEDDFEHQPIISTRYAASGLLLVAALALSTLARHMDHEDRVIF 845
            :....|......:|   |....||..||.:                             |.|
  Fly   410 NDLNPHGLSRELVMAGWQHCSKLEIMFEKE-----------------------------EQR--- 442

  Fly   846 KWKTEVAEQKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNF 910
              ..|:.:..|.|:..:::.:.|:|:::|..:||..     |..::...||:.||.|:|..:.|.
  Fly   443 --SDELEKSLELADSWKRQGDELLYSMIPRPIAERM-----RLSEEQVCQSFEEVSVIFLEVMNV 500

  Fly   911 SDFYSEETVNN-QG-LECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASG---INVQRT 970
            .|    |.:|: || ::.:..||:|.|..|..:..|   .:.|::|:|..|||.||   :|
  Fly   501 YD----EGLNSIQGAMQTVNTLNKVFSALDEEIISP---FVYKVETVGMVYMAVSGAPDVN---- 554

  Fly   971 VRNDAPITERWSHLAILVEFALELKHALQSINEQSFNHFVLKMGINHGPITAGVIGARKPHYDIW 1035
                 |:     |.....:.||.:   ::...........:::|||.||:.|||:|.:.|.|.::
  Fly   555 -----PL-----HAEHACDLALRV---MKKFKAHDMGDVAIRVGINSGPVVAGVVGQKVPRYCLF 606

  Fly  1036 GNTVNVASRMESTGKAGAIQVTEETCNILRLFGYTFLQRGLVAVKGKGQLMTFYL 1090
            |:|||.||||||:.....||:::.|.:.:|..||....||.|.|||||.:.|::|
  Fly   607 GDTVNTASRMESSSDPWKIQLSKYTGDKVRQVGYKVESRGTVQVKGKGDMETYWL 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AcyC	122..455	CDD:441717	11/39 (28%)
		Guanylate_cyc	294..476	CDD:425528	15/70 (21%)
		Guanylate_cyc	892..1092	CDD:425528	68/204 (33%)
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:462233
		HNOBA	218..476	CDD:462234	68/435 (16%)
		Nucleotidyl_cyc_III	485..662	CDD:448371	68/201 (34%)