DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac3 and CG31183

DIOPT Version :9

Sequence 1:	NP_610116.2	Gene:	Ac3 / 35419	FlyBaseID:	FBgn0023416	Length:	1167	Species:	Drosophila melanogaster
Sequence 2:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	78/247 - (31%)
Similarity:	141/247 - (57%)	Gaps:	27/247 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   851 VAEQKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYS 915
            |.|:.:..::.:::.|.|:|.:||..||...:     |...:.::::.:|.:.|:.:..|:...:
  Fly   908 VEERTQDYHEEKKKCEKLLYQLLPQSVAAQLI-----SGQPVVAETFDQVTIYFSDIVGFTAISA 967

  Fly   916 EETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRNDAPITER 980
            |.|    .::.::|||::.:.||:::|  .| |:.|::|||..||..||:          ||...
  Fly   968 EST----PMQVVQFLNDLYTCFDSIVE--NF-DVYKVETIGDAYMVVSGL----------PIRNG 1015

  Fly   981 WSHLAILVEFALELKHALQS--INEQSFNHFVLKMGINHGPITAGVIGARKPHYDIWGNTVNVAS 1043
            ..|...:...||.|..|:.:  |:.:..:...|::|::.|...|||:|.:.|.|.::|:|||.||
  Fly  1016 NQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTAS 1080

  Fly  1044 RMESTGKAGAIQVTEETCNILRLFGYTFL--QRGLVAVKGKGQLMTFYLQGK 1093
            ||||.|:|..|.::|.|...|..|| ||:  :||.|.:||||:::|::|:|:
  Fly  1081 RMESNGEALKIHISETTKEALDEFG-TFVTTRRGFVPMKGKGEMLTYWLEGE 1131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831
		CYCc	256..453	CDD:214485
		Guanylate_cyc	294..476	CDD:278633
		CYCc	860..1071	CDD:214485	64/212 (30%)
		Guanylate_cyc	892..1092	CDD:278633	67/203 (33%)
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003	9/29 (31%)
		CYCc	917..1108	CDD:214485	65/213 (31%)
		Guanylate_cyc	944..1130	CDD:278633	67/203 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454035
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740