Protein Alignment Ac3 and Gyc32E

DIOPT Version :9

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Alignment Length: 1206
• Identity: 244/1206 - (20%)
• Similarity: 436/1206 - (36%)
• Gaps: 367/1206 - (30%)

  Fly    90 DQSAPTRVINCCMLLAYLALTALLHIGRRSDKPALRR--FHQILLIIVPRA------LWLLSILH 146
            |:|..|..     |||....|.:|.. :.||.....:  ||.....:.|.:      :.||:..|
  Fly   118 DESCTTEA-----LLASAWNTPMLSF-KCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFH 176

  Fly   147 ---FTVYVILQP---SFSPRDLLGWAILLNFLVYVTLPLQLIFLGLSIGCITYFICLS--LPV-- 201
               |::.|..:|   |...|.:...|...||                  .|::|..:|  :|.
  Fly   177 WNKFSIVVSSKPIWGSDVARAIQELAEARNF------------------TISHFKYISDYIPTTK 223

  Fly   202 GYSHWDSLLSNQLAANAVLIATAALIGLLYYFMGEAKQKRAFLEAKKSLEVKMVIEEQSAEQERL 266
            ..|..|.::....|...:           |.|:||              .:.||...:..:..||
  Fly   224 TLSQIDKIIEETYATTRI-----------YVFIGE--------------HIAMVDFVRGLQNRRL 263

  Fly   267 LLSVLPKHVAIKMREDLGSSSSEA------FKKIYMSRHENVSILYADIVGFTA---ISSTY--- 319
            |.|  ..::.:.:.:::..|:...      :...|:.:.::.|:   |.:.|.:   ||.||
  Fly   264 LES--GDYIVVSVDDEIYDSNRRVNIMERNYLDPYIRKEKSKSL---DKISFRSVIKISMTYPQN 323

  Fly   320 -SAQDLVKMLNELFARFDRLAEKYQQ-----LRIKILGDCYYCISGAPDERPDHAVLCVHMGLSM 378
             ..:|:...:.: :||.......|.|     :.:.|.|...|          |..::       .
  Fly   324 PHIRDICSKIKD-YARKTPFLVPYHQRVFDNISVPIYGLHLY----------DSVMI-------Y 370

  Fly   379 VKAIKYVQQKANSPVDMRVG--IHTGAVLAGILGQRQWQ----FDVYSKDVELANKMESSGKAGR 437
            |:||..|         :|:|  |:.|.::...:..|.:.    ||||         ::|:|.|.
  Fly   371 VRAITEV---------LRLGGDIYDGNLVMSHIFNRSYHSIQGFDVY---------IDSNGDAE- 416

  Fly   438 VHISDKTLAFLNGEFEVEAAFGEKREELLRIAGLKTYFITKVVKAF--------------ASPCA 488
               .:.|:..|..:....|:.|...:..::..|...|....|:..|              ..|.|
  Fly   417 ---GNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLA 478

  Fly   489 KKINETQAEIAHPNPNGSTTDIVSDEDDNDATLDDEELLAQNSVSNGHQIGIAVTADEEEQVKLE 553
            :.:.....|:. |...                ||...|:      :|....:.|.......:|..
  Fly   479 EPLCGFHGELC-PRKK----------------LDWRYLV------SGPLCALVVVVAIALLIKHY 520

  Fly   554 NFKQRLKDELVTRDGHENLTKDTNIFL--RFKNPQLEQLYAVYREPYSSLPLLAALLVQCIDVLY 616
            .::|.|...|...|     .||..:..  .:.||..:.::.:.|:
  Fly   521 RYEQTLAGLLWKVD-----MKDVTVINLGEYNNPTNKNIFQICRQ-------------------- 560

  Fly   617 SYLVL----PRSTLHFINIAAPLVPIAMLVVISLAESFSG------MLPKFFVDVSKRF-NDITF 670
            |.||:    .||   |.|||.                |.|      .:.|..||:::.. .::..
  Fly   561 SILVVGEPNKRS---FTNIAL----------------FRGNIVAMKKIHKKSVDITRSIRKELKL 606

  Fly   671 VRELAAIIIALTIGFS----NVIDMFFFVTFV---RTEHIVSESEFNV----TASLESDINLVVE 724
            :||:....|...||.|    :||   .|.|:.   ..|.:::..:.::    .:||.|||   ::
  Fly   607 MREVRHENIINFIGASTDHGSVI---IFTTYCARGSLEDVLANEDLHLDHMFISSLVSDI---LK 665

  Fly   725 GMV--------------TAEHLLPASFV---------------------------------EQMR 742
            ||:              ::..|:.:.:|                                 |.:|
  Fly   666 GMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQEEPNKSELELKRALCMAPELLR 730

  Fly   743 DAVPTERVLYPSYLSNFGVLILIAIA-------------VIAQLTHLTKILL--LLSIAALHCYF 792
            ||....|......:.:||:|:...|.             .|.|.....::|.  :...|..|.:.
  Fly   731 DAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALTHTHL 795

  Fly   793 NI--FIMQDL-YALEDDFEHQPIISTRYAASGLL-LVAALALSTLARHMDHEDRVIFKWKTEVAE 853
            :|  :|.:.| ...::|.|.:|.|  |.....|. |.|.|..:.....:...::..:..:..|.|
  Fly   796 DIPDYIRKCLCQCWDEDPEVRPDI--RLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQE 858

  Fly   854 QKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEET 918
            :.....:.:::.:.|:|.:||..|||...:.     |.:.::.:..|.:||:.:..|::..:..|
  Fly   859 RTNLLYEEKKKTDMLLYQMLPRPVAELLKRG-----DPVEAECFDCVTILFSDIVGFTELCTTST 918

  Fly   919 VNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRNDAPITERWSH 983
                ..|.:..||:..:..|:::   ...|:.|::|||..||..||:.:|...|          |
  Fly   919 ----PFEVVEMLNDWYTCCDSII---SNYDVYKVETIGDAYMVVSGLPLQNGSR----------H 966

  Fly   984 LAILVEFALELKHALQSINEQSFNH-----FVLKMGINHGPITAGVIGARKPHYDIWGNTVNVAS 1043
            ...:...||   |.|:::......|     ..|::|::.||..|||:|.:.|.|.::|:|||.||
  Fly   967 AGEIASLAL---HLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTAS 1028

  Fly  1044 RMESTGKAGAIQVTEETCNILRLFG-YTFLQRGLVAVKGKGQLMTFYLQGKSQSSAEPVASGVVV 1107
            ||||||.:..|.::|.|..:|::.| |..::|||.::||||.:.|::|..:.|....|
  Fly  1029 RMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKRQQPELTP------- 1086

  Fly  1108 LNGQDSSAVESTSELEASDIKMPLLKMNGPEQSLEI 1143
                |..:...|.:...|          ||.:|:|:
  Fly  1087 ----DLISTVDTLDTYCS----------GPRESMEV 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831	31/173 (18%)
		CYCc	256..453	CDD:214485	40/220 (18%)
		Guanylate_cyc	294..476	CDD:278633	39/199 (20%)
		CYCc	860..1071	CDD:214485	62/216 (29%)
		Guanylate_cyc	892..1092	CDD:278633	63/205 (31%)
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	80/423 (19%)
		ANF_receptor	59..427	CDD:279440	77/402 (19%)
		PHA02988	534..826	CDD:165291	62/343 (18%)
		PK_GC-A_B	550..832	CDD:270944	59/328 (18%)
		HNOBA	<847..886	CDD:285003	9/38 (24%)
		CYCc	865..1057	CDD:214485	62/216 (29%)
		Guanylate_cyc	892..1076	CDD:278633	62/203 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740