Protein Alignment Ac3 and CG32305

DIOPT Version :10

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Alignment Length: 1240
• Identity: 308/1240 - (24%)
• Similarity: 520/1240 - (41%)
• Gaps: 338/1240 - (27%)

  Fly   100 CCMLLAYLALTALLHIGRRSDKPALRRFHQILLIIVPRALWLLSILHFTVYVILQP-----SFSP 159
            |..|...||.:.|..:...|:  .::....:.|::|...:.||:::...:.|.:.|     .|||
  Fly    33 CQNLRLELACSRLRELALMSN--VVQIIWHVELLMVAHVILLLALVKDIILVTMVPYFAVMLFSP 95

  Fly   160 ---------------RDLLGWAILLNFL--------------------------------VYVTL 177
                           ..|:.|.:.| ||                                ||:||
  Fly    96 FIMLLSMQNNVGMITNTLISWLMAL-FLTSMDLVSDLLGTIYSGAAYPTVPCYDHVVLVSVYMTL 159

  Fly   178 PLQLIFLGLSIGCITYFICLSLPVGYSHWDSLLSNQ-----LAANAVLIATAALIGLLYYFMGEA 237
            |: ..:.|.|:..:...:.: :.:||:.:...|::|     ||:.|:.:.|..||...:..:.:.
  Fly   160 PI-AFYQGSSVYVLGMVVSI-IYIGYAFYMQYLNDQVSFYLLASYAIYLFTLNLIFSFFTIIRDY 222

  Fly   238 KQKRAFLEAKKSLEVKMVIEEQSAEQERLLLSVLPKHVAIKMREDLGS----------SSSEAFK 292
            ..:||.|...:.:...:|.:....::..||.|:||:.:...::|::.|          .|....:
  Fly   223 GLRRAILSRYQLVYQNIVYQLVMKKENGLLESILPRKMIRTLQEEICSRIEDQDKNFTPSKAGLR 287

  Fly   293 KIYMSRHENVSILYADIVGFTAISSTYSAQDLVKMLNELFARFDRLAEKYQQLRIKILGDCYYCI 357
            |:::..:.|||||.||:|.:|.:::|..|..||::|::||..||..|.:.:.:|||.|||.|.|:
  Fly   288 KLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEILHDLFVNFDLAANRNRAMRIKFLGDSYNCV 352

  Fly   358 SGAPDERPDHAVLCVHMGLSMVKAIKYVQQKANSPVDMRVGIHTGAVLAGILGQRQWQFDVYSKD 422
            :|.|:..|.||..||...|.|:...:.|..:....:::|:|:|:|.|.|||:|..:||||::|||
  Fly   353 AGIPNYFPAHASCCVDQALEMIHITQGVSSRRELDINLRIGVHSGEVFAGIIGHTKWQFDIWSKD 417

  Fly   423 VELANKMESSGKAGRVHISDKTLAFLNGEF----EVEAAFGEKREELLRIAGLKTYFITKVVKAF 483
            |::.|::||||..|.||:|.:||:.|:..:    ..|||   |.:.:|:.||::|:.::..:...
  Fly   418 VDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREGTEAA---KNDPILQQAGIRTFLVSNRLPDA 479

  Fly   484 ASPCAKKINETQAEIAHPNPNGSTTDIVSDEDDNDATLDDEELLAQNSVSN------GHQIGIAV 542
            ..|                                ..||||  |:..|:::      |:.
  Fly   480 VEP--------------------------------GELDDE--LSSASINSCRLSYGGYY----- 505

  Fly   543 TADEEEQVKLENFKQRLKDELVTRDGH--------ENLTK-DTNIFLRFKNPQLEQLYAVYRE-- 596
               ||.|:|.:....:..|::..  ||        .::.| |.|....|.| |:..:..|:|.
  Fly   506 ---EEIQIKAQREIMKEVDQMAV--GHCFIEWRRSSSMKKQDFNEEYLFSN-QIHLVLGVFRSWK 564

  Fly   597 ---PYSSLPLL----AALLVQCIDV-LYSYLVLPRSTLHFINIAAPLVPIAMLVVISLAESF--- 650
               .:.:||.|    ..|||.|..: :.|..::..:|  :.:|...|..:.:|:::.:...:
  Fly   565 REWEFHNLPDLMIKYTMLLVLCAGLAIMSINLIEEAT--YPDILVLLGILLILLILCILAGYKKL 627

  Fly   651 -------------SGMLPKFFVDVSKRFNDITFVRELAAIIIALTIGFSNVIDMFFFVTFVRTEH 702
                         |..|.::.:.:|:|..|..|||      |.||:    |:.:..:|
  Fly   628 RLQWKKLTPMSQPSCFLSRWLLRISERIEDSLFVR------IPLTM----VVLLLLYV------- 675

  Fly   703 IVSESEFNV-TASLESDINLVVEGMVTAEHLLPASFVEQMRDAVPTERVLY--PSYLSNFG---- 760
            :.|::.|:. .|.||..|                           .|..||  .||...||
  Fly   676 MSSQAVFSCDVAKLELSI---------------------------IEAHLYNEKSYAECFGPWTV 713

  Fly   761 ----VLILIAIAVIAQLTHLTKIL-----LLLSIAALHCYFNIFIMQDLYALEDDFEHQPIISTR 816
                |:::..:.|:.....:.|||     |.|.:..:|.|:.       :|.|........:.:.
  Fly   714 TYCVVIVISLLFVVPGCPLVIKILAGLLILGLHLGTVHLYYG-------FAFERSETTDLGLKSD 771

  Fly   817 YAASGLLLVAALALSTLARHMDHEDRVIFKWKTEVAEQKETANDMRQRNEALVYNVLPVHVAEHF 881
            ||.:..|:...:.|....||:::..:..:..:....|..:..::..:..:.::.|:||.|||:.:
  Fly   772 YAHTWYLVALFIVLVLRERHVNYLRKFNYFMRVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVY 836

  Fly   882 MKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLECLRFLNEVISDFDALL-ELPQ 945
              ..:|.||.||.:::::|.|:|||:.||          |.....||.|:|:|..||.|| :...
  Fly   837 --KVRRPHDQLYYENFSKVAVMFASIENF----------NADTAGLRILHEIICCFDDLLVDYQT 889

  Fly   946 FQDIIKIKTIGSTYMAASGINVQR--TVRNDAPITE----------------------------- 979
            ...|.|||.:|.|||.|.|:....  ....|.|:.:
  Fly   890 RYKIEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGD 954

  Fly   980 -------RWSHLAILV--EFALELKHALQSINE----QSFNHFV---LKMGINHGPITAGVIGAR 1028
                   :...:|:||  ||||:|...:..|..    ..::.|:   ||:||:||.:.|||:|..
  Fly   955 NVSQPYAQVQDVAVLVMTEFALDLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLS 1019

  Fly  1029 KPHYDIWGNTVNVASRMESTGKAGAIQVTEETCNILRLFGYTFLQRGLVAVKGKGQLMTF----- 1088
            ||||||||:|||:||||.|||....||||..|..:||.|......||...|||.|::.|:
  Fly  1020 KPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQFNIRCNYRGHTEVKGVGKVPTYLVVVD 1084

  Fly  1089 ---------------------------------YLQGKSQSSAEPVASGVVVLNGQDSSAVESTS 1120
                                             ::..||.:|.|..|.|.:..|      |....
  Fly  1085 PDLTFQDHDQVSMSMKDSKSWVIDTLSLSFTPSFVPPKSSTSDEEEAEGELEEN------VSEGD 1143

  Fly  1121 ELEAS 1125
            |||.|
  Fly  1144 ELEVS 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AcyC	122..455	CDD:441717	110/403 (27%)
		Guanylate_cyc	294..476	CDD:425528	74/185 (40%)
		Guanylate_cyc	892..1092	CDD:425528	84/285 (29%)
CG32305	NP_728725.2	AcyC	62..451	CDD:441717	110/391 (28%)
		Nucleotidyl_cyc_III	292..445	CDD:448371	66/152 (43%)
		Nucleotidyl_cyc_III	845..1081	CDD:448371	84/245 (34%)