DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ac3 and Gucy2c

DIOPT Version :9

Sequence 1:NP_610116.2 Gene:Ac3 / 35419 FlyBaseID:FBgn0023416 Length:1167 Species:Drosophila melanogaster
Sequence 2:NP_037302.1 Gene:Gucy2c / 25711 RGDID:2771 Length:1072 Species:Rattus norvegicus


Alignment Length:376 Identity:100/376 - (26%)
Similarity:169/376 - (44%) Gaps:76/376 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   799 DLYAL-----EDDFEHQP----IISTRYAASGLL-----------LVAALALSTLARHMDHEDRV 843
            ::|.|     |:|.|.:|    |.||.....||.           |:..|.|  .:|:::|    
  Rat   718 EVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQL--YSRNLEH---- 776

  Fly   844 IFKWKTEVAEQKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMP 908
                  .|.|:.:.....|.|.:.|.:.:||..|    :|:.|.. ..:..:.|.||.:.|:.:.
  Rat   777 ------LVEERTQLYKAERDRADHLNFMLLPRLV----VKSLKEK-GIVEPELYEEVTIYFSDIV 830

  Fly   909 NFSDFYSEETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRN 973
            .|:......|    .:|.:..||::...||.:::   ..|:.|::|||..|:.|||:.::...|:
  Rat   831 GFTTICKYST----PMEVVDMLNDIYKSFDQIVD---HHDVYKVETIGDAYVVASGLPMRNGNRH 888

  Fly   974 DAPITERWSHLAI-LVEF--ALELKHALQSINEQSFNHFVLKMGINHGPITAGVIGARKPHYDIW 1035
            ...|    |.:|: ::.|  ..||:| |..:      ...:::|::.||..|||:|.:.|.|.::
  Rat   889 AVDI----SKMALDILSFMGTFELEH-LPGL------PVWIRIGVHSGPCAAGVVGIKMPRYCLF 942

  Fly  1036 GNTVNVASRMESTGKAGAIQVTEETCNILRLFGYTFLQ--RGLVAVKGKGQLMTFYLQG------ 1092
            |:|||.||||||||....|.::..|..|||.....||.  ||...:||:|...|::|.|      
  Rat   943 GDTVNTASRMESTGLPLRIHMSSSTIAILRRTDCQFLYEVRGETYLKGRGTETTYWLTGMKDQEY 1007

  Fly  1093 --------KSQSSAEPVASGVVV--LNGQDSSAVESTSELEASDIKMPLLK 1133
                    ::|...:...|.::|  |..:.:|.|:|......:..|...|:
  Rat  1008 NLPTPPTVENQQRLQTEFSDMIVSALQKRQASGVKSRRPTRVASYKKGFLE 1058

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ac3NP_610116.2 AC_N <127..285 CDD:292831
CYCc 256..453 CDD:214485
Guanylate_cyc 294..476 CDD:278633
CYCc 860..1071 CDD:214485 63/213 (30%)
Guanylate_cyc 892..1092 CDD:278633 64/204 (31%)
Gucy2cNP_037302.1 Periplasmic_Binding_Protein_Type_1 34..414 CDD:299141
PKc_like 479..749 CDD:304357 9/30 (30%)
STYKc 501..744 CDD:214568 8/25 (32%)
CYCc 787..978 CDD:214485 63/213 (30%)
Guanylate_cyc 814..1001 CDD:278633 64/204 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.