| Sequence 1: | NP_610116.2 | Gene: | Ac3 / 35419 | FlyBaseID: | FBgn0023416 | Length: | 1167 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055835.2 | Gene: | PHLPP2 / 23035 | HGNCID: | 29149 | Length: | 1323 | Species: | Homo sapiens |
| Alignment Length: | 713 | Identity: | 140/713 - (19%) |
|---|---|---|---|
| Similarity: | 242/713 - (33%) | Gaps: | 214/713 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 554 NFKQRLKDELVTRDGHENLTKDTNIFLRFKNPQLEQLYAVYREPYSSLPLLAALLV--QCIDVLY 616
Fly 617 SYLVLPRSTLHFINIAAPLVPIAMLVVISLAESFSGMLPKFFVDVSKRFNDITFVRELAAI---- 677
Fly 678 --------IIALTI-GFS--------------NVIDMFFFVTFVRTEHIVSE------SEFNVTA 713
Fly 714 SLESDINLVVEGMVTAEHLLPASFVEQMRDAVPTERVLYPSYLSNFGVLILIAIAVIAQLTH--L 776
Fly 777 TKILLLLSIAALHCYFNIFIMQDLYALEDDFEHQP----------IISTRYAASGLL-------L 824
Fly 825 VAALALSTLARHMDHEDRVIF-KWKTEVAEQKETANDMRQRNEALVYNVLPVHVAEHFMKNTKRS 888
Fly 889 HDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLECLRFLNEVISDFDALLELPQFQ------ 947
Fly 948 -DIIKI-------------KTIGSTYMAA--------SGINVQRTVRNDAPITER------WSHL 984
Fly 985 AILVEFALEL-KHALQSINEQSFNHFVLKMGINHGPITAGVIGARKPHYDIWGNTVNVASRMEST 1048
Fly 1049 GKAGAI-----QVTEETCNILRLFGYTFLQRGLVAVKGKGQLMTFYLQGKSQSSAEPVAS-GVVV 1107
Fly 1108 LNGQDSSAVESTSELEASDIKMPLLKM----NGPEQSLEIDQDRSLRNDSAGQESVAECQSLL 1166 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ac3 | NP_610116.2 | AC_N | <127..285 | CDD:292831 | |
| CYCc | 256..453 | CDD:214485 | |||
| Guanylate_cyc | 294..476 | CDD:278633 | |||
| CYCc | 860..1071 | CDD:214485 | 46/250 (18%) | ||
| Guanylate_cyc | 892..1092 | CDD:278633 | 43/239 (18%) | ||
| PHLPP2 | NP_055835.2 | PH_PHLPP-like | 149..243 | CDD:270131 | |
| LRR 1 | 250..271 | ||||
| leucine-rich repeat | 253..273 | CDD:275380 | |||
| LRR 2 | 273..296 | ||||
| leucine-rich repeat | 274..300 | CDD:275380 | |||
| LRR 3 | 300..321 | ||||
| leucine-rich repeat | 301..323 | CDD:275380 | |||
| LRR_RI | 313..606 | CDD:238064 | 58/289 (20%) | ||
| LRR_8 | 322..380 | CDD:290566 | 9/36 (25%) | ||
| LRR 4 | 323..344 | ||||
| leucine-rich repeat | 324..346 | CDD:275380 | |||
| LRR 5 | 346..368 | 6/18 (33%) | |||
| leucine-rich repeat | 347..369 | CDD:275380 | 7/19 (37%) | ||
| LRR 6 | 369..390 | 4/26 (15%) | |||
| leucine-rich repeat | 370..416 | CDD:275380 | 12/53 (23%) | ||
| LRR 7 | 392..412 | 5/20 (25%) | |||
| LRR 8 | 416..439 | 4/28 (14%) | |||
| leucine-rich repeat | 418..440 | CDD:275380 | 3/27 (11%) | ||
| LRR 9 | 440..460 | 5/20 (25%) | |||
| leucine-rich repeat | 442..461 | CDD:275380 | 5/19 (26%) | ||
| LRR 10 | 461..480 | 2/18 (11%) | |||
| leucine-rich repeat | 462..481 | CDD:275380 | 3/18 (17%) | ||
| LRR 11 | 481..502 | 3/20 (15%) | |||
| leucine-rich repeat | 482..503 | CDD:275380 | 2/20 (10%) | ||
| LRR 12 | 503..524 | 3/20 (15%) | |||
| leucine-rich repeat | 504..526 | CDD:275380 | 4/21 (19%) | ||
| LRR 13 | 526..547 | 6/23 (26%) | |||
| leucine-rich repeat | 527..549 | CDD:275380 | 6/24 (25%) | ||
| LRR_8 | 549..606 | CDD:290566 | 12/71 (17%) | ||
| LRR 14 | 549..570 | 3/28 (11%) | |||
| leucine-rich repeat | 550..565 | CDD:275380 | 2/22 (9%) | ||
| LRR 15 | 571..592 | 5/20 (25%) | |||
| leucine-rich repeat | 572..595 | CDD:275380 | 6/22 (27%) | ||
| LRR 16 | 595..616 | 4/27 (15%) | |||
| leucine-rich repeat | 596..645 | CDD:275380 | 9/48 (19%) | ||
| LRR 17 | 621..644 | 5/22 (23%) | |||
| LRR_8 | 645..703 | CDD:290566 | 19/105 (18%) | ||
| LRR_4 | 645..685 | CDD:289563 | 9/46 (20%) | ||
| LRR 18 | 645..666 | 5/22 (23%) | |||
| leucine-rich repeat | 646..669 | CDD:275380 | 5/24 (21%) | ||
| LRR 19 | 669..690 | 5/30 (17%) | |||
| leucine-rich repeat | 670..692 | CDD:275380 | 5/31 (16%) | ||
| LRR 20 | 692..713 | 10/56 (18%) | |||
| leucine-rich repeat | 693..714 | CDD:275380 | 10/56 (18%) | ||
| LRR 21 | 714..735 | 4/20 (20%) | |||
| leucine-rich repeat | 715..734 | CDD:275380 | 3/18 (17%) | ||
| LRR 22 | 737..758 | 2/20 (10%) | |||
| leucine-rich repeat | 738..764 | CDD:275380 | 4/25 (16%) | ||
| PP2Cc | 784..1033 | CDD:238083 | 39/197 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1060..1157 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1285..1323 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2114 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||