Protein Alignment Ac3 and gcy-27

DIOPT Version :9

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 143/660 - (21%)
• Similarity: 238/660 - (36%)
• Gaps: 196/660 - (29%)

  Fly   544 ADEEEQVKLENFKQRLKDE---LVTR----DGHENLTKDTNIFLRFK--------NPQLEQLYAV 593
            ||...|.:|||  :..|||   |.:|    ..:..:......|::|:        |..|:.||.:
 Worm    50 ADARMQRELEN--RTAKDEANALTSRRRVFGSYALIGTQRAEFIQFRQIKHIDITNASLDFLYNL 112

  Fly   594 YREPYSSLPLLAALLVQCIDVLYSYLVLPRSTLHFINIAAPLVPIAMLVVISLAESFSGM----L 654
            .:..:.:|...             |.:.....|:.:.|...||....|....|...| ||    .
 Worm   113 KQLKHDNLANF-------------YGIQLNDDLNTMTILHALVERGTLEEFCLDRDF-GMDETFK 163

  Fly   655 PKFFVDVSK-----RFNDITFVRELAAIIIALTIGFSNVIDMFFFVTFVRTEHIVSESEFNVTAS 714
            ..|..|:.|     ..:.:.:...|.|....:.|.:...|.::....|| .::..:|   |:|..
 Worm   164 SAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNFV-CDNFDAE---NITMP 224

  Fly   715 LESDINLVVEGMV--TAEHL--------LPASFVEQMRDAVPTERVLYPSYLSNFGVLILIAIAV 769
            ..||..:.....|  ..||:        ||..||...:.
 Worm   225 DRSDYTISYAQYVCFPPEHIREYDATGKLPTRFVRGSKQ-------------------------- 263

  Fly   770 IAQLTHLTKILLLLSIAALHCYFNIFIMQDLYALEDDFEHQPIISTRYAASGLLLVAALALSTLA 834
                            ..::|...||.|.    :|.:..::.|.|.....|||::
 Worm   264 ----------------GDIYCVGMIFYMM----IEREDPYRLIHSVERPGSGLMM---------- 298

  Fly   835 RHMDH------------EDRVIFK----WKTEVAEQKETANDMR-------------------QR 864
            ..:||            ||.::.|    |..: .|::.|..::|                   :.
 Worm   299 EILDHNLMPFISNNETQEDTLLDKCKECWNRD-PEKRPTIENLRNAIAICYADSKGNLIDQMIRM 362

  Fly   865 NE-------------------------ALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLF 904
            ||                         .|:..:||..:|:. :||...:.    ::|||...|:|
 Worm   363 NEKYADELETLVAARSADLALAQMQTMRLLNEMLPASIAKD-LKNGVIAP----ARSYASATVMF 422

  Fly   905 ASMPNFSDFYSEETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQR 969
            ..:.:|..........    |.:.|||::...||.:::.   .|..|::|.|.|||.|||:
 Worm   423 VQICDFIVILKRRPPK----EVIGFLNDIFDQFDTVIKR---HDAYKVETTGETYMVASGV---- 476

  Fly   970 TVRNDAPITERWSHLAILVEFALELKHALQSINEQSFNHFVL--KMGINHGPITAGVIGARKPHY 1032
                  |......|:..:.|.:||::....|...::..::.|  ::|.:.|||.|||||.:.|.|
 Worm   477 ------PNENEGRHVFEVAEMSLEIRAISLSYTLENDKNYKLRVRIGFHAGPIAAGVIGIKNPRY 535

  Fly  1033 DIWGNTVNVASRMESTGKAGAIQVTEETCN-ILRLFGYTFLQRGLVAVKGKGQLMTFYLQGKSQS 1096
            .::|:|||.||||:|......||.:|.|.. :|....|..::||:|.|||||::..::|......
 Worm   536 CLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHEYKLVKRGIVHVKGKGEVNCYWLNEHIHK 600

  Fly  1097 SAEPVASGVV 1106
            ..|...||.:
 Worm   601 DEEIEESGTI 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831
		CYCc	256..453	CDD:214485
		Guanylate_cyc	294..476	CDD:278633
		CYCc	860..1071	CDD:214485	64/257 (25%)
		Guanylate_cyc	892..1092	CDD:278633	64/202 (32%)
gcy-27	NP_001255957.2	PKc_like	75..338	CDD:304357	56/337 (17%)
		CYCc	383..573	CDD:214485	60/211 (28%)
		Guanylate_cyc	411..595	CDD:278633	63/204 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910