Protein Alignment Ac3 and LOC101884360

DIOPT Version :10

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: XP_073800254.1
• Gene: LOC101884360 / 101884360
• -ID: -
• Length: 1401
• Species: Danio rerio
• Alignment Length: 1276
• Identity: 355/1276 - (27%)
• Similarity: 554/1276 - (43%)
• Gaps: 331/1276 - (25%)

  Fly    52 HVLNELYHNYSIKQRRSGLKWFVF---AAALFNIWTIGIPWDQSA----------PTR--VINCC 101
            ::|.|........|.|...:..:|   ||:|  :|  |:.:..:|          ||.  ::.||
Zfish   101 NILEEACRERCFPQTRRRFRCVLFYLAAASL--LW--GLFFMANANRCERTAFLLPTASFLLLCC 161

  Fly   102 MLLAYLALTALLHIGRRSDKPALRRFHQILLIIVPRALWLLSILHFTVYV--------------- 151
            :|..:......:|...::         .:|||:|..||.|...:..:.:.
Zfish   162 VLFVFTFTRFYVHCYNQA---------SLLLIVVTFALTLAPQIQTSGFSDFNAPPLKDEDDDFS 217

  Fly   152 ----------------ILQPSFSPRDLLGWAILLNFLVYVTLPLQLIFLGLSIGCITYFICLSLP 200
                            ::.|..||.......:.:..|:|..|.:: .:..|.:|.|  :..|...
Zfish   218 GAEDKNLTFEATQSGDLVTPCLSPVGTFSLGMEVLSLLYSFLHVR-FYASLLLGLI--YSVLFET 279

  Fly   201 VGYSH--WDSLLSNQ-----------LAANAVLIATAALIGLLYYFMGEAKQKRAFLEAKKSLEV 252
            :|:.|  .|:..||.           :...|:|...|.:||:..:.|.|.:.:..||:..:::..
Zfish   280 LGWMHLIQDNRWSNSTEEHLETLYWLIPGRAILHVCAHIIGIHLFIMSEVRSRSTFLKVGQAIMH 344

  Fly   253 KMVIEEQSAEQERLLLSVLPKHVA---IKMRED---------------LGSSSSEA--------- 290
            ...:|.:.|.:||::.||:|:.||   :|..:|               .|:||.::
Zfish   345 GKDLEVEKALKERMIHSVMPRRVADELMKQGDDDNDNSVKRYSTGAAIAGASSPKSAKRKKTSIP 409

  Fly   291 -----FKKIYMSRHENVSILYADIVGFTAISSTYSAQDLVKMLNELFARFDRLAEKYQQLRIKIL 350
                 |:...|.|.|.||||:|||||||.:|:..||..||.:||:||.|||||.|.....:|..|
Zfish   410 RGQIIFRPFNMKRMEPVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCELTCCEKISTL 474

  Fly   351 GDCYYCISGAPDERPDHAVLCVHMGLSMVKAIKYVQQKANSPVDMRVGIHTGAVLAGILGQRQWQ 415
            ||||||::|.|:.|.|||..||.|||.|::||:...|:....|:||||||||.||.||||.::::
Zfish   475 GDCYYCVAGCPEPREDHAYCCVEMGLGMIQAIEQFCQEKKEMVNMRVGIHTGTVLCGILGMKRFK 539

  Fly   416 FDVYSKDVELANKMESSGKAGRVHISDKTLAFLNGEFEVEAAFGEKREEL------LRIAGLKTY 474
            |||:|.||.|||.||..|.||:||:|:.|..||:..:..|.  |...|.:      .::.|||||
Zfish   540 FDVWSNDVNLANLMEQLGVAGKVHLSEATDKFLDDRYLRED--GRVTERIGPSVVADQLKGLKTY 602

  Fly   475 FIT----KVVKAFASPCAKKINETQAEIAHPNPN-----GSTTD-------------IVSDED-- 515
            .|:    |:.:..:.|...:|..:.:..:. :|:     |:.||             :::.||
Zfish   603 LISGRKVKLCQWMSPPPPSEIRASVSSSSF-SPDVSASAGAPTDAPDRAKSACPSCSLITSEDGL 666

  Fly   516 --DNDATLDDEELLAQNSVSNGH--------------------QIGIAVTADEEEQ--------- 549
              .|..| |.|...:.:.|..|.                    |..:.....::|:
Zfish   667 VHSNSCT-DPEHKTSNSKVPAGRGPKSVNGLLSPGVEQPLTHSQTSLCEMLQDKEKKWPAVGGGT 730

  Fly   550 --------VKLENFKQRLKDELVTRDGHENLTKDTNIFLRFKNPQLEQ---------LYAVYREP 597
                    ::.:||::|.....|.....::|.||     .|..|.:.:         |.:.||..
Zfish   731 MDHSALIPLRSKNFRERSDAHFVDVIKEDSLMKD-----YFYRPPINKLSHTFIDRSLESAYRTS 790

  Fly   598 Y-------------------SSLPLL------AALLVQC-IDVLYSYLVLPRSTLHFINIAAPLV 636
            |                   |.|.:|      .||.:.| :..|.::..||...|....:||.|.
Zfish   791 YQDEVKTQTPVQTFASPTFSSFLDMLLCCCVFLALSLACFLRPLVTHQPLPTPALIVAAVAALLE 855

  Fly   637 PIAMLVVI--------------SLAESFSGMLPKFFVDVSKRFNDITFVRELAAIIIALTIGFSN 687
            .:|:::.|              :|....||.:|:..:               .|::::|.
Zfish   856 CLALILAIRRAFYLDSVLNCTRTLLWVISGWIPRHMI---------------GAVLVSLP----- 900

  Fly   688 VIDMFFFVTFVRTEHIVSESEFNVTASLESDINL-------VVEGMVTAEHLLPASFVEQMRDAV 745
            .|.:|        .||        |.::...|..       |:..::...:....||  .||.
Zfish   901 AIAVF--------SHI--------TCNMHDSIQFTMFTCCAVIIAIIQYCNFCQLSF--WMRS-- 945

  Fly   746 PTERVLYPSYLSNFGVLILIAIAVIAQLTHLTKILLLLSIAALHCYFNIFI-MQDLYALEDDFEH 809
                                ::|.:|.||.|:    :|.......:..:|: ..||.:..:|.:.
Zfish   946 --------------------SLATLAGLTFLS----VLWSPPCSTWEQLFLRSNDLNSSINDIQS 986

  Fly   810 --------QPIISTRYAASGLLLVAALALSTLARHMDHEDRVIFKWKTEVAEQKETANDMRQRNE 866
                    |.::......:..||:  |.:..|.|..:...|:.:....|..:.:....:||.:.:
Zfish   987 SAEEPSRLQDLLGPEALVAFFLLL--LLVWFLNREFEVSYRLHYHGNVEADQHRIKIQNMRDQAD 1049

  Fly   867 ALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLECLRFLN 931
            .|:.|::|:||||. :|.|:.     ||:::..|||:|||:.|||:||.|.  ...|.||.|.||
Zfish  1050 WLLRNIIPIHVAEQ-LKVTQS-----YSKNHDNVGVIFASIVNFSEFYEES--YEGGKECYRVLN 1106

  Fly   932 EVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRNDAPITERWSHLAILVEFALELKH 996
            |:|.|||.||....|.:|.||||||:|||||||:|.|:....:.|    .:||..|.||:||:..
Zfish  1107 ELIGDFDELLRKSDFSNIEKIKTIGATYMAASGLNTQQCSDQNHP----HAHLRALFEFSLEMMR 1167

  Fly   997 ALQSINEQSFN-HFVLKMGINHGPITAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEET 1060
            .:...|:.... .|.|::|.||||:||||||..|..|||||:|||:||||::||....:||:||:
Zfish  1168 VVDDFNKNMLGFKFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRVQVSEES 1232

  Fly  1061 CNILRLFGYTFLQRGLVAVKGKGQLMTFYLQGKSQSSAEPV 1101
            ..:|....|.|..||.|.||||||:.| ||..||..|. ||
Zfish  1233 YCVLSGMDYEFDYRGTVNVKGKGQMKT-YLYPKSADSG-PV 1271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AcyC	122..455	CDD:441717	133/408 (33%)
		Guanylate_cyc	294..476	CDD:425528	95/187 (51%)
		Guanylate_cyc	892..1092	CDD:425528	100/200 (50%)
LOC101884360	XP_073800254.1	None