Protein Alignment Ac3 and gucy2g

DIOPT Version :9

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: XP_009305067.2
• Gene: gucy2g / 100333350
• ZFINID: ZDB-GENE-130531-70
• Length: 1127
• Species: Danio rerio
• Alignment Length: 995
• Identity: 213/995 - (21%)
• Similarity: 380/995 - (38%)
• Gaps: 244/995 - (24%)

  Fly   244 LEAKKSLEVKMVIEEQSAEQERLLLSVLPK----HVAIKMREDLGSSSSEAFKKIYMSRHENVSI 304
            |.:|.::.:.:..:....||.:..|.::.|    .|.:...||..:...|| :|:.:...|.|.:
Zfish   202 LRSKVTVTMGIKFDTSDLEQAKRNLQIISKVARVVVVLANAEDSTAMMIEA-QKLGLMSGEYVFL 265

  Fly   305 LY--------ADIVGFTAISSTYSAQDLVKMLNELFARFDRLAEK----------YQQLRIKILG 351
            |.        .|.:..|::|.|  .:.::|..:.:|.    ||||          :.|...|:.|
Zfish   266 LVQQFEVSGKVDNLWKTSVSET--NRTMLKAFDMVFV----LAEKSYDGYDYYDFFDQAYDKLKG 324

  Fly   352 DCYYCISGAPDERPDH------AVLCVHMGLSMV----KAIKY---VQQKANSPVDMRVGIHTGA 403
            |.:|....:..|...:      |||...|||...    |.|::   :.||......:|....:|.
Zfish   325 DPFYSNLSSVKEVSSYAAYLHDAVLLYAMGLKEAFKSGKDIRHGREIVQKLRDRTSIRFYGASGL 389

  Fly   404 VLAGILGQRQWQFDVYSKDVELANKM---------ESSGKAGRVHISDKTLAFLNGE-------- 451
            |.....|:|...:.||  |::....:         :|..|..:..:....:.:.||:
Zfish   390 VHFDEYGERNLDYSVY--DLQQTETLIQFVSVLDFDSHTKMIKPTLRFSNIVWQNGKPPTDNPSC 452

  Fly   452 -FEVEAAFGEKRE----------ELLRIAGLKTYFITKVVKAFASPCAKK-----INETQAEIAH 500
             |:.|.......|          .|:.:|.:....:..:.|........:     ||.:...|..
Zfish   453 GFDNELCEWLDNEISLLVLLVALPLIGVAAVSLITLLTLQKLRLQSRLDESNWWLINYSDITILR 517

  Fly   501 PNPNGSTTDIVSDEDDNDATLDDEELLAQNSVSNGHQIGIAVTADEEEQVKLENFKQRLKDELVT 565
             .|.|:....|:.......:...:.:|:.||.:....|...|...:..:|.:    :.||::::.
Zfish   518 -EPKGTQILSVNTTPSKCGSGGSQSMLSSNSCNTREAIYATVGLFQGNEVGI----KYLKNQIIP 577

  Fly   566 RDGHENLTKDTNIFLRFKNPQLEQLYAVYREPYSSLPLLAALLVQC-----IDVL---------- 615
            .....::..:.|:....|:..|.|.:.|..:|    |.:..::..|     .|||
Zfish   578 DIKKPSIIAEFNMLKEMKHENLVQFFGVCIDP----PNVCIVMQYCKKGSLKDVLGNHEIDLDWM 638

  Fly   616 ----YSY-LVLPRSTLHFINIAA--PLVPIAMLVVISLAESFSG-------------MLPKFFVD 660
                ::| :|.....:|..::.:  .|.|...||...|....||             ::|   :|
Zfish   639 FKLSFAYDIVNGMEYIHKSSLKSHGNLRPSTCLVDSRLQIKLSGFGLWEFKCGTKHRLIP---LD 700

  Fly   661 VSKRFNDI-----TFVRELAAIIIALTIGFSNVIDMFFFVTFVRTEHIVSESEFNVTASLESDIN 720
             |.::.::     .|:||:.........|     |::.|...:|      |..::.......|:
Zfish   701 -SPKYEEMYWTAPEFLREIFYPFNGTQKG-----DVYSFAIIIR------ELIYSTEVGPYHDV- 752

  Fly   721 LVVEGMVTAEHLLPASFVEQMRDAVPTERVLYPSYLSNFGVLILIAIAVIAQLTHLTKILLLLSI 785
                      ||.|...::|:|..: :|..|.|:         |.|.....:|..|.|.
Zfish   753 ----------HLEPKEIIKQLRTPM-SEEPLRPT---------LSADICDERLIPLIKA------ 791

  Fly   786 AALHCYFNIFIMQDLYALEDDFEHQPIIST-----RYAA----SGLLLVAALALSTLARHMDHED 841
                |:            .::.:|:|...:     |.|.    :.:|......|...|.|::
Zfish   792 ----CW------------SENPDHRPPFGSIRRQLRDACPESHANILDNMVNKLEKYANHLE--- 837

  Fly   842 RVIFKWKTEVAEQKETANDM-RQRNEALVYNVLPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFA 905
                    ||.|::.:...: :.|.:.|:.::||.::|:..|     :...:..:||..|.:.|:
Zfish   838 --------EVVEERTSQLTVEKSRADKLLSSMLPRYIADQLM-----AGKSVEPRSYEMVTIFFS 889

  Fly   906 SMPNFSDFYSEETVNNQGLECLRFLNEVISDFDALLELPQFQDIIKIKTIGSTYMAASGINVQRT 970
            .:..|:...|.    :..||.:..||::.|.||.:::|   .|:.|::|||..||.|||:
Zfish   890 DIVGFTTMCSV----SSALEVVTLLNDLYSLFDDIIKL---YDVYKVETIGDAYMVASGL----- 942

  Fly   971 VRNDAPITERWSHLAILVEFALELKHALQSINEQSFNH-----FVLKMGINHGPITAGVIGARKP 1030
                 ||:....|...:...||   |.|.||......|     ..|::|||.||:.|||:|:..|
Zfish   943 -----PISNGTLHAEEISTMAL---HFLSSIKRFKIRHLPNERLALRIGINSGPVVAGVVGSTMP 999

  Fly  1031 HYDIWGNTVNVASRMESTGKAGAIQVTEETCNILRLFG-YTFLQRGLVAVKGKGQLMTFYLQGKS 1094
            .|.::|:|||.||||||......|.:::.|.:||...| :...:||.:.:||||...||:|..|.
Zfish  1000 RYCLFGDTVNTASRMESNSLPLKIHISQSTADILLTIGTFELEERGDIEIKGKGTQKTFWLLSKP 1064

  Fly  1095 QSSAEPVASGVVVLNGQDSS 1114
            ..:..|        .||||:
Zfish  1065 GFTFPP--------TGQDSN 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831	9/44 (20%)
		CYCc	256..453	CDD:214485	51/249 (20%)
		Guanylate_cyc	294..476	CDD:278633	46/240 (19%)
		CYCc	860..1071	CDD:214485	67/217 (31%)
		Guanylate_cyc	892..1092	CDD:278633	70/205 (34%)
gucy2g	XP_009305067.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810