Protein Alignment Ac3 and adcy7

DIOPT Version :9

• Sequence 1: NP_610116.2
• Gene: Ac3 / 35419
• FlyBaseID: FBgn0023416
• Length: 1167
• Species: Drosophila melanogaster
• Sequence 2: NP_001106549.1
• Gene: adcy7 / 100127741
• XenbaseID: XB-GENE-1005225
• Length: 1061
• Species: Xenopus tropicalis
• Alignment Length: 1074
• Identity: 377/1074 - (35%)
• Similarity: 557/1074 - (51%)
• Gaps: 170/1074 - (15%)

  Fly   103 LLAYLALTALLHIGRRSDKPALRRFHQILLIIVPRALWLL----SILHFTVYVILQPSFSPRDLL 163
            |:.:.||..|::......| .||.|..::.|.:....::|    |::|            ..|.:
 Frog    74 LVVFCALYILVYTESFVQK-WLRVFSLVIYICLLTIGYVLTYDSSVVH------------AWDQV 125

  Fly   164 GWAILLNFLVYVTLPL--QLIFLGLSIGCITYFICLSLPVGYSHW-DSLLSNQLAANAVLIATAA 225
            .:.:.:.|.||..|||  |...:...|..|::.|.:|:.|..|.. :..::.||.||||:.....
 Frog   126 PFFLFITFSVYTMLPLGMQACLIVSIISGISHIIVISITVVLSSGSNDAIAFQLMANAVIFLCGN 190

  Fly   226 LIGLLYYFMGEAKQKRAFLEAKKSLEVKMVIEEQSAEQERLLLSVLPKHVAIKMREDLGSSSSEA 290
            |:|..:.:..:...:..:....|.:.:||.:|.:..:||.|||||||.:::::|:..:....:|.
 Frog   191 LMGAYHKYHMQDASRDLYSYTVKCIRIKMKLELKKRQQESLLLSVLPVYISMEMKLAIQDRLTET 255

  Fly   291 ---------FKKIYMSRHENVSILYADIVGFTAISSTYSAQDLVKMLNELFARFDRLAEKYQQLR 346
                     |..:|:.||:|||||||||||||.::|..|.::||.||||||.:||::|::.:.:|
 Frog   256 NDNRQPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVMLNELFGKFDQIAKENECMR 320

  Fly   347 IKILGDCYYCISGAPDERPDHAVLCVHMGLSMVKAIKYVQQKANSPVDMRVGIHTGAVLAGILGQ 411
            ||||||||||:||.|...|::|..||.|||.:.:|||.|::...:.::||||:|:|.||.|::|.
 Frog   321 IKILGDCYYCVSGLPVSLPNNAKNCVKMGLDICEAIKQVREATGADINMRVGVHSGNVLCGVIGL 385

  Fly   412 RQWQFDVYSKDVELANKMESSGKAGRVHISDKTLAFLNGEFEVEAAFGEKREELLRIAGLKTYFI 476
            |:|||||:|.||.|||:|||:|..|||||::.||..:||.::||...||.|:..|:...:||:.:
 Frog   386 RKWQFDVWSHDVSLANRMESAGLPGRVHITEATLKHMNGAYDVEEGHGELRDPYLKEMNIKTFLV 450

  Fly   477 TKVVKAFASPCAKKINETQAEIAHPNPN------------------GSTTDIVSDEDDNDATLDD 523
                   ..|.||........:.....|                  |:.... |..|..||:..:
 Frog   451 -------IDPRAKNSRVKNNHLTRHRVNDGIKVRPSVRMTRYLESWGAARPF-SHFDQTDASSTE 507

  Fly   524 EELLAQNSVSNGH---QI---GIAVTADEEEQV-KLENFKQRLKDELV-TRDGHENL------TK 574
            ...:      ||.   :|   |:..|...|..| :..|.::.|.|.:: |.||..:.      |.
 Frog   508 VPTV------NGKPKPEIPLKGMGRTVKTERNVSQKRNQEEELHDRMMNTIDGLSSAKPWFGKTD 566

  Fly   575 DTNIFLRFKNPQ-LEQLYAVYREP-YSSLPLLAALLVQCIDVLYSYLVLPRSTLHFINIAAPLVP 637
            |...||.|.... ||:.|..:|.| ..|..|.|:|:..|| .|...||:|||.  .:.|:..:|.
 Frog   567 DFYGFLLFFTADGLEKEYRTFRIPCIQSYFLCASLIFLCI-FLIQILVMPRSA--NLGISFGVVS 628

  Fly   638 IAMLVVISLAESFSGMLPKFFVDVSKRF--NDITFVRELAAII-------------IALTIGFSN 687
            :.:|.|:.:.          :||...||  .:..|.|.|.:::             :|||:|...
 Frog   629 VLILWVLLIC----------YVDKCARFCNENAPFSRFLCSLVEMIETRPSLRVPLVALTLGSLL 683

  Fly   688 VIDMFFFVTFVRTEHIVSESEFNVTASLESDINLVVEGMVTAEHLLPASF-VEQMRDAVPTERVL 751
            :|                           |.:||.::  .|.:....:|. .|....::|
 Frog   684 II---------------------------SIVNLPLD--QTLQTCNTSSIATESQCQSIP----- 714

  Fly   752 YPSYLSNFGVLILIAIAVIAQLTHLTKILLL------LSIAALHCYFNIF---IMQDLYALEDDF 807
            |..|..   :|.|:|.::..::....|||||      .::...|.:.:||   :...:..|| ||
 Frog   715 YYVYCC---ILGLVACSMFLRMCFELKILLLTAAFTAYNVIIFHTHSSIFRSNLNSSIGVLE-DF 775

  Fly   808 EHQPIISTRYAASGLLLVAALALSTLARHMDHEDRVIFKWKTEVAEQKETANDMRQRNEALVYNV 872
            :.   :|..|     |.:..|.|..|||.:::..|:...||.:..::.|....|...|:.|:.||
 Frog   776 QK---MSCFY-----LSLYYLTLVLLARQVEYYSRLDCLWKRKFRKEDEEIETMENLNQLLLENV 832

  Fly   873 LPVHVAEHFMKNTKRSHDDLYSQSYAEVGVLFASMPNFSDFYSEETVNNQGLECLRFLNEVISDF 937
            ||.|||.:|: :..||::|||.|||..|.|:|||:|.|..||:|..||.:||||||.|||:|:||
 Frog   833 LPAHVAAYFI-DDNRSNEDLYHQSYDCVCVMFASVPEFKVFYTECDVNKEGLECLRLLNEIIADF 896

  Fly   938 DALLELPQFQDIIKIKTIGSTYMAASGINVQRTVRNDAPITERWSH--LAILVEFALELKHALQS 1000
            |.||..|:|..:.||||||||||||:|:.......|.   .:...|  :.|.||:|:.|...|..
 Frog   897 DELLMKPKFSGVEKIKTIGSTYMAATGLTATPGQENQ---DQEKQHALIGITVEYAMALMSKLDG 958

  Fly  1001 INEQSFNHFVLKMGINHGPITAGVIGARKPHYDIWGNTVNVASRMESTGKAGAIQVTEETCNILR 1065
            ||..|||:|.|::||||||:.||||||:||.||||||||||||||||||:.|.||||||||.||.
 Frog   959 INRHSFNNFRLRVGINHGPVIAGVIGAKKPQYDIWGNTVNVASRMESTGELGKIQVTEETCQILE 1023

  Fly  1066 LFGYTFLQRGLVAVKGKGQLMTFYL---QGKSQS 1096
            ..||:...||.:.|||||:|.|:::   ..||||
 Frog  1024 GLGYSCECRGFINVKGKGELRTYFVCTDMAKSQS 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac3	NP_610116.2	AC_N	<127..285	CDD:292831	41/164 (25%)
		CYCc	256..453	CDD:214485	102/205 (50%)
		Guanylate_cyc	294..476	CDD:278633	97/181 (54%)
		CYCc	860..1071	CDD:214485	121/212 (57%)
		Guanylate_cyc	892..1092	CDD:278633	116/204 (57%)
adcy7	NP_001106549.1	AC_N	<21..266	CDD:318454	49/204 (24%)
		Guanylate_cyc	268..418	CDD:306677	85/149 (57%)
		DUF1053	483..591	CDD:399378	27/114 (24%)
		Guanylate_cyc	851..1048	CDD:306677	116/199 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910