DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nompB and Hop3

DIOPT Version :9

Sequence 1:	NP_724347.3	Gene:	nompB / 35414	FlyBaseID:	FBgn0016919	Length:	857	Species:	Drosophila melanogaster
Sequence 2:	NP_001031620.1	Gene:	Hop3 / 826849	AraportID:	AT4G12400	Length:	558	Species:	Arabidopsis thaliana

Alignment Length:	719	Identity:	143/719 - (19%)
Similarity:	235/719 - (32%)	Gaps:	266/719 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 AEALSKAKEAFSLDRTLHQFRDQHGENVYHNFDLTYAQYERSEMHIEALNTYSIMAKN--KMFPH 210
            |.|::...||.:|..|.|        .:|.|...:||...|.|   |||:.    ||.  ::.|.
plant    19 ATAITHFTEAINLSPTNH--------ILYSNRSASYASLHRYE---EALSD----AKKTIELKPD 68

  Fly   211 VNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKS---------LSQLRLKIRENIGILFIRMGS 266
            .::....:|..:..:..:.:||..|:..|:..|.:         .|:.|:..:.|         .
plant    69 WSKGYSRLGAAFIGLSKFDEAVDSYKKGLEIDPSNEMLKSGLADASRSRVSSKSN---------P 124

  Fly   267 YSDAASSFE-------------------FIMTERANIRSSIHLLLCYF-------ALGDVEKVKL 305
            :.||....|                   |:.|.:...|:..:|.| |.       |||.:..||
plant   125 FVDAFQGKEMWEKLTADPGTRVYLEQDDFVKTMKEIQRNPNNLNL-YMKDKRVMKALGVLLNVK- 187

  Fly   306 AFRRLCDVQTEAIESDMESETNIIKLQQQAEPIQQIGETDGYQSLNNEPVTGSVIKAEGGGKLNE 370
             |.......||..|:|...|.     :.:.||: ::.|.:..:....|    ..:|.:|.|.:..
plant   188 -FGGSSGEDTEMKEADERKEP-----EPEMEPM-ELTEEERQKKERKE----KALKEKGEGNVAY 241

  Fly   371 TVK-FAATVKHRYVVQALKKDELAVYRNERRNAVKRSITMIVDLISPFIEDNYNDGYNWCIEIIK 434
            ..| |...|:|  ..:|::.|:                           ||
plant   242 KKKDFGRAVEH--YTKAMELDD---------------------------ED-------------- 263

  Fly   435 TSNLAWLANELELNKALVYLRQNDVHQAIETLQM-----YDRKSEGSMTASALTNLSFIYIKMAS 494
               :::|.     |:|.|||......:.||....     .:.:|:..|.|.|||......:|||
plant   264 ---ISYLT-----NRAAVYLEMGKYEECIEDCDKAVERGRELRSDFKMIARALTRKGSALVKMA- 319

  Fly   495 HCVNQLHEIGSLKNNAPGLINAGIVELGSHNLILASERFEGALQ-LQPMNFEARYNLGLVALAQN 558
            .|                                 |:.||.|:: .|....|.|....|..|  |
plant   320 RC---------------------------------SKDFEPAIETFQKALTEHRNPDTLKKL--N 349

  Fly   559 DYELAEERFELLKEQLMLPSSVQHSHVFYQLAKLQERRLESGLISNFTPGAALQAYLQVVGISAS 623
            |.|..::  ||.:::...|:..:           :||
plant   350 DAEKVKK--ELEQQEYFDPTIAE-----------EER---------------------------- 373

  Fly   624 DIDSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAV 688
                   ||....::: |.:.||.::|:||.:.|.:|:...|:..:.|.||.|....|...|:.:
plant   374 -------EKGNGFFKE-QKYPEAVKHYSEAIKRNPNDVRAYSNRAACYTKLGALPEGLKDAEKCI 430

  Fly   689 LADPNDPNLMLRIASCFRNSY-------LPTKQY---LGLFQKIHARFPDNLTCI----RALMQV 739
            ..||:           |...|       ...|:|   :..:|:.....|.|...:    |.:.|:
plant   431 ELDPS-----------FTKGYSRKGAIQFFMKEYDKAMETYQEGLKHDPKNQEFLDGVRRCVEQI 484

  Fly   740 TKS----LELGDLYERYAS-----EYTRLQSQQQERQSEQRYQQQRFPSAAKFSNRLRSIRQSNE 795
            .|:    |...:|.||.|.     |...:.|....||....:|:.  |.||             :
plant   485 NKASRGDLTPEELKERQAKAMQDPEVQNILSDPVMRQVLVDFQEN--PKAA-------------Q 534

  Fly   796 EHLK 799
            ||:|
plant   535 EHMK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompB	NP_724347.3	TPR_11	213..275	CDD:290150	11/70 (16%)
		TPR repeat	213..240	CDD:276809	4/26 (15%)
		TPR	216..244	CDD:197478	5/27 (19%)
		TPR repeat	245..279	CDD:276809	7/61 (11%)
		TPR repeat	284..309	CDD:276809	10/31 (32%)
		TPR repeat	479..502	CDD:276809	8/22 (36%)
		TPR repeat	509..539	CDD:276809	4/30 (13%)
		TPR_16	<529..568	CDD:290168	12/39 (31%)
		TPR repeat	544..568	CDD:276809	7/23 (30%)
		TPR_11	626..692	CDD:290150	17/65 (26%)
		TPR repeat	627..655	CDD:276809	8/27 (30%)
		TPR repeat	660..690	CDD:276809	8/29 (28%)
Hop3	NP_001031620.1	TPR_11	2..67	CDD:290150	18/62 (29%)
		TPR repeat	2..30	CDD:276809	4/10 (40%)
		TPR repeat	35..65	CDD:276809	12/44 (27%)
		TPR_11	38..101	CDD:290150	17/69 (25%)
		TPR_1	70..103	CDD:278916	6/32 (19%)
		TPR repeat	70..98	CDD:276809	4/27 (15%)
		TPR_11	229..292	CDD:290150	19/113 (17%)
		TPR repeat	234..258	CDD:276809	7/25 (28%)
		TPR repeat	263..293	CDD:276809	9/51 (18%)
		TPR_12	264..337	CDD:290160	23/111 (21%)
		TPR_1	267..292	CDD:278916	8/29 (28%)
		TPR repeat	305..336	CDD:276809	13/64 (20%)
		TPR_11	369..434	CDD:290150	19/111 (17%)
		TPR repeat	369..397	CDD:276809	10/74 (14%)
		TPR_1	375..402	CDD:278916	8/27 (30%)
		TPR_11	402..468	CDD:290150	15/76 (20%)
		TPR repeat	402..432	CDD:276809	8/29 (28%)
		TPR_1	403..436	CDD:278916	9/43 (21%)
		TPR repeat	437..465	CDD:276809	4/27 (15%)
		TPR_1	438..470	CDD:278916	5/31 (16%)
		STI1	507..546	CDD:128966	11/47 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000