Protein Alignment Lamp1 and CD68

DIOPT Version :10

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001242.2
• Gene: CD68 / 968
• HGNCID: 1693
• Length: 354
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 65/282 - (23%)
• Similarity: 116/282 - (41%)
• Gaps: 39/282 - (13%)

  Fly    47 NPLTSSSSTISTSSTTTEKPITT-RSTSTITPRSTTPSTESPSTTAPVISTTIAPQPYPQP---- 106
            :|.::|::|....||.|..|.|| ...:|:.|.|.:.:| ||..|:........|.|.|.|
Human    92 HPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTAT-SPGFTSSAHPEPPPPSPSPSPTSKE 155

  Fly   107 SIG--AWNTS---CIMLQMAAQLNFTYEAREGNFTTGLYNIPSNASVEDAECKSQTTQFI----- 161
            :||  .|...   |:.||...|:...|..:.|....|:..:..|.:.....|:......:
Human   156 TIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPY 220

  Fly   162 -HLIWGPETSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDAKENQTVQLITRSDGAFKTPEN 225
             ||.:|.....|..::|         ||:|.:...:   .||.|.: .|......|....:.|..
Human   221 GHLSFGFMQDLQQKVVY---------LSYMAVEYNV---SFPHAAQ-WTFSAQNASLRDLQAPLG 272

  Fly   226 MSYHCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFSVGHDCDSSETSDVVPIAVGI 290
            .|:.|:. ..|.::..:..:.|       .::::|.:..:...|.....| .|:.|.::|:.:|:
Human   273 QSFSCSN-SSIILSPAVHLDLL-------SLRLQAAQLPHTGVFGQSFSC-PSDRSILLPLIIGL 328

  Fly   291 ALAALILVVLISYLCARRRSTS 312
            .|..|:.:|||::...|||.::
Human   329 ILLGLLALVLIAFCIIRRRPSA 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	106..262	CDD:480752	32/170 (19%)
CD68	NP_001242.2	Mucin-like	23..140		16/48 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..162		22/70 (31%)
		2 X 30 AA tandem repeats	70..129		12/36 (33%)
		Lamp	156..303	CDD:460152	31/167 (19%)