Protein Alignment Lamp1 and LAMP2

DIOPT Version :9

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001116078.1
• Gene: LAMP2 / 3920
• HGNCID: 6501
• Length: 411
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 76/308 - (24%)
• Similarity: 131/308 - (42%)
• Gaps: 72/308 - (23%)

  Fly    38 VSDLFLEQANPLTS-------------------SSSTISTSSTTTEKPITTRSTSTITP--RSTT 81
            ::|||  :.|.|::                   .:.|:||:....:|.    .|||:.|  .:|.
Human   147 LNDLF--RCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFLCDKD----KTSTVAPTIHTTV 205

  Fly    82 PSTESPSTTAPVISTTIAPQPYPQPSIGAW-----NTSCIMLQMAAQLNFTYEAREGNFTTGLYN 141
            |   ||:||         |.|..:|..|.:     |.:|::..|..|||.|.:.     ...:.|
Human   206 P---SPTTT---------PTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDK-----VASVIN 253

  Fly   142 IPSNASVEDAECKSQTTQFIHLIWGPETSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDAKE 206
            |..|.:.....|:|.|..   |.....|.|....::..|:.:...|..:.|.:.|:
Human   254 INPNTTHSTGSCRSHTAL---LRLNSSTIKYLDFVFAVKNENRFYLKEVNISMYLV--------- 306

  Fly   207 NQTVQLITRSDGAF-KTPENMSYHCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFS 270
            |.:|..|..::.:: ..|...||.|.:.|.::::....       |:...::|:.| ......:|
Human   307 NGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQ-------INTFDLRVQPF-NVTQGKYS 363

  Fly   271 VGHDCDS-SETSDVVPIAVGIALAALILVVLISYLCARRRSTSRGYMS 317
            ...:|.: |:.:.::|:|||:||..||:||.|||:..||:|.: ||.|
Human   364 TAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRT-GYQS 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	<77..318	CDD:279622	64/250 (26%)
LAMP2	NP_001116078.1	Lamp	110..411	CDD:279622	76/308 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12295
eggNOG	1	0.900	-	-		E1_KOG4818
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I5121
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002671
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11506
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.920