Protein Alignment Lamp1 and LAMP3

DIOPT Version :10

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: XP_005247417.1
• Gene: LAMP3 / 27074
• HGNCID: 14582
• Length: 418
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 72/282 - (25%)
• Similarity: 128/282 - (45%)
• Gaps: 38/282 - (13%)

  Fly    45 QANPLTSSSSTISTS---STTTEKPI-TTRSTSTITPRSTTPSTESPSTTAPVISTTIAPQPYPQ 105
            |.:..|:..:|:|.:   |||.:||: .|.:..|......|..|.:|::|.|  ..|:|||| ..
Human   161 QPSNQTTLPATLSIALHKSTTGQKPVQPTHAPGTTAAAHNTTRTAAPASTVP--GPTLAPQP-SS 222

  Fly   106 PSIGAW---NTS--CIMLQMAAQLNFTYEAREGNFTTGLY-NIPSNASVEDAECKSQTTQFIHLI 164
            ...|.:   |.|  ||..:|..||  ..:.:|..|:...| ||..||:.....|.::.:..:...
Human   223 VKTGIYQVLNGSRLCIKAEMGIQL--IVQDKESVFSPRRYFNIDPNATQASGNCGTRKSNLLLNF 285

  Fly   165 WGPETSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDAKENQTV-QLITRSDGAFKTPENMSY 228
            .|...:     :.|.|..::..:|.:..:|.:        .:.:|: |.|..:...|:|....|:
Human   286 QGGFVN-----LTFTKDEESYYISEVGAYLTV--------SDPETIYQGIKHAVVMFQTAVGHSF 337

  Fly   229 HCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFSVGHDCDSSETSDVVPIAVGIALA 293
            .|...|.:.::..|.       :..:.||::|| ...|..|....:|.|......:|:|:|:::.
Human   338 KCVSEQSLQLSAHLQ-------VKTTDVQLQAF-DFEDDHFGNADECFSDRNRREIPVAMGLSIT 394

  Fly   294 ALILVVLISYLCARRRSTSRGY 315
            .|::::|.:.|.||:| .||||
Human   395 GLLVILLTACLVARKR-PSRGY 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	106..262	CDD:480752	33/162 (20%)
LAMP3	XP_005247417.1	Lamp	224..366	CDD:460152	34/164 (21%)