Protein Alignment Lamp1 and LAMP5

DIOPT Version :9

• Sequence 1: NP_610111.3
• Gene: Lamp1 / 35411
• FlyBaseID: FBgn0032949
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_036393.1
• Gene: LAMP5 / 24141
• HGNCID: 16097
• Length: 280
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 47/218 - (21%)
• Similarity: 83/218 - (38%)
• Gaps: 43/218 - (19%)

  Fly   113 TSCIMLQMAAQLNFTYEAREGNFTTGLYNIPSNASVEDAECKSQ---TTQFIHLIW--------- 165
            |:|:|.:.||:....|:....|:...:......|....||.|.:   :...:.:.|
Human    55 TTCLMAEFAAKFIVPYDVWASNYVDLITEQADIALTRGAEVKGRCGHSQSELQVFWVDRAYALKM 119

  Fly   166 -----------GPE-TSKQSLIMYFNKSNDTTVLSFMQIHLALLPEDFPDAKENQTVQLITRSDG 218
                       ||| |.:.|.:.:...|::.|              .|.||.........:....
Human   120 LFVKESHNMSKGPEATWRLSKVQFVYDSSEKT--------------HFKDAVSAGKHTANSHHLS 170

  Fly   219 AFKTPENMSYHCTRVQKINMTETLDAEQLIGWISVSHVQVEAFRRANDTGFSVGHDC---DSSET 280
            |..||...||.|...|.|::..: |.::.:..| :|.|.::.|...:|..||..|.|   :..:.
Human   171 ALVTPAGKSYECQAQQTISLASS-DPQKTVTMI-LSAVHIQPFDIISDFVFSEEHKCPVDEREQL 233

  Fly   281 SDVVPIAVGIALAALILVVLISY 303
            .:.:|:.:|:.|..:|:|.|..|
Human   234 EETLPLILGLILGLVIMVTLAIY 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamp1	NP_610111.3	Lamp	<77..318	CDD:279622	47/218 (22%)
LAMP5	NP_036393.1	Lamp	<40..229	CDD:307462	40/189 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4818
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11506
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910