Protein Alignment CG17571 and KLK4

DIOPT Version :10

• Sequence 1: NP_610109.1
• Gene: CG17571 / 35409
• FlyBaseID: FBgn0259998
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 83/261 - (31%)
• Similarity: 128/261 - (49%)
• Gaps: 29/261 - (11%)

  Fly     4 LLLSVVALVALAASCHGNPGLDFPFGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETVL 68
            |:|.|...: ::.||          .:|:||||....:.|:|.:: ..:...||.|.|:..:.||
Human    15 LILGVAGSL-VSGSC----------SQIINGEDCSPHSQPWQAAL-VMENELFCSGVLVHPQWVL 67

  Fly    69 TAAHCMQSYAASELQVRVGSTSRSSGGEVVTVRAFKYHEGYNSKLMINDVAIIKLSSPVRQTSKI 133
            :||||.|:.....|.:......:..|.::|.......|..||..|:.||:.:|||...|.::..|
Human    68 SAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTI 132

  Fly   134 RAIELADSEAVSGTNAVVSGWGTTCFLFCSS--PDTLQKVEVDLLHYKDCAA--DTYNYGSDSIL 194
            |:|.:|.....:|.:.:|||||    |..:.  |..||.|.|.::..:.|:.  |...:.|
Human   133 RSISIASQCPTAGNSCLVSGWG----LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS---- 189

  Fly   195 ETMVCATG--EKKDACQGDSGGPLVADNKLVGVVSWGSG-CAWTGYPGVYADVASLRSWIVDTTD 256
              |.||.|  ::||:|.|||||||:.:..|.|:||:|.. |...|.||||.::.....||..|..
Human   190 --MFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252

  Fly   257 S 257
            :
Human   253 A 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_610109.1	Tryp_SPc	30..251	CDD:214473	75/227 (33%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	77/229 (34%)