Protein Alignment CG17571 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_610109.1
• Gene: CG17571 / 35409
• FlyBaseID: FBgn0259998
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 98/272 - (36%)
• Similarity: 132/272 - (48%)
• Gaps: 40/272 - (14%)

  Fly    11 LVALAAS-CHGNPGLDFPFGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETVLTAAHCM 74
            :|:|..| |...|    ...|||.|:.|....:|:|.|| .....|.||||::....|:||||||
Human   201 VVSLRCSECGARP----LASRIVGGQSVAPGRWPWQASV-ALGFRHTCGGSVLAPRWVVTAAHCM 260

  Fly    75 QSYAASEL---QVRVGSTSRSSGGEVVTVRAFKYHEG-----------YNSKLMINDVAIIKLSS 125
            .|:..:.|   :|..|..|.|         |.:.|:|           |:::....|||:::|.:
Human   261 HSFRLARLSSWRVHAGLVSHS---------AVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQT 316

  Fly   126 PVRQTSKIRAIELADSEA--VSGTNAVVSGWGTTCFLFCSSPDTLQKVEVDLLHYKDCAADTYNY 188
            .:..:..:.|:.|...|.  ..|:...|||||.|......|.|.||...|.|...:.|.:.....
Human   317 ALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYS 381

  Fly   189 GSDSILETMVCA--TGEKKDACQGDSGGPLVADN----KLVGVVSWGSGCAWTGYPGVYADVASL 247
            |  ::...|:||  ...:.||||||||||||..:    :||||||||.|||...:|||||.||..
Human   382 G--ALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEF 444

  Fly   248 RSWIVDTT-DSL 258
            ..||.||. |||
Human   445 LDWIHDTAQDSL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_610109.1	Tryp_SPc	30..251	CDD:214473	86/242 (36%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	4/11 (36%)
		Tryp_SPc	217..448	CDD:214473	86/242 (36%)