DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17571 and KLK6

DIOPT Version :9

Sequence 1:NP_001286096.1 Gene:CG17571 / 35409 FlyBaseID:FBgn0259998 Length:258 Species:Drosophila melanogaster
Sequence 2:NP_001012982.1 Gene:KLK6 / 5653 HGNCID:6367 Length:244 Species:Homo sapiens


Alignment Length:259 Identity:87/259 - (33%)
Similarity:132/259 - (50%) Gaps:31/259 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LLSVVALVALAASCHGNPGLDFPFGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETVLT 69
            |:.|::|:|.|.:...|        ::|:|...|..::|||.::.|: |...|||.||....|||
Human     4 LMVVLSLIAAAWAEEQN--------KLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLT 59

  Fly    70 AAHCMQSYAASELQVRVGS---TSRSSGGEVVTVRAFKYHEGYNSKLMINDVAIIKLSSPVRQTS 131
            ||||.:    ..|||.:|.   ..|.|..|..:|.....|..|::.....|:.:::|:.|.:.:.
Human    60 AAHCKK----PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120

  Fly   132 KIRAIELADSEAVSGTNAVVSGWGTTC---FLFCSSPDTLQKVEVDLLHYKDCAADTYNYGSDSI 193
            .|:.:.|....:.:.|:..:.|||.|.   |     |||:|...:.|:..::|   .:.| ...|
Human   121 LIQPLPLERDCSANTTSCHILGWGKTADGDF-----PDTIQCAYIHLVSREEC---EHAY-PGQI 176

  Fly   194 LETMVCATGEK--KDACQGDSGGPLVADNKLVGVVSWGS-GCAWTGYPGVYADVASLRSWIVDT 254
            .:.|:||..||  ||:||||||||||..:.|.|:||||: .|.....||||.:|....:||..|
Human   177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17571NP_001286096.1 Tryp_SPc 30..251 CDD:214473 78/229 (34%)
Tryp_SPc 31..254 CDD:238113 80/231 (35%)
KLK6NP_001012982.1 Tryp_SPc 23..237 CDD:214473 78/227 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8473
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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