DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17571 and PRSS2

DIOPT Version :9

Sequence 1:	NP_001286096.1	Gene:	CG17571 / 35409	FlyBaseID:	FBgn0259998	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001290343.1	Gene:	PRSS2 / 5645	HGNCID:	9483	Length:	261	Species:	Homo sapiens

Alignment Length:	273	Identity:	104/273 - (38%)
Similarity:	142/273 - (52%)	Gaps:	36/273 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRLLLSVVALVALAASCHGNPGLDFPF---GRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLI 62
            ||.||:......|:||          ||   .:||.|...:..:.|||||:.:  |.||||||||
Human     1 MNLLLILTFVAAAVAA----------PFDDDDKIVGGYICEENSVPYQVSLNS--GYHFCGGSLI 53

  Fly    63 DSETVLTAAHCMQSYAASEL----------QVRVGSTSRS--SGGEVVTVRAFKY--HEGYNSKL 113
            ..:.|::|.||.:|...|:|          |||:|..:..  .|.|.. :.|.|.  |..|||:.
Human    54 SEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQF-INAAKIIRHPKYNSRT 117

  Fly   114 MINDVAIIKLSSPVRQTSKIRAIELADSEAVSGTNAVVSGWGTTCFLFCSSPDTLQKVEVDLLHY 178
            :.||:.:||||||....|::.||.|..:...:||.:::||||.|.......||.||.::..:|..
Human   118 LDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQ 182

  Fly   179 KDCAADTYNYGSDSILETMVCA--TGEKKDACQGDSGGPLVADNKLVGVVSWGSGCAWTGYPGVY 241
            .:|.|   :| ...|...|.|.  ....||:||||||||:|::.:|.|:||||.|||....||||
Human   183 AECEA---SY-PGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVY 243

  Fly   242 ADVASLRSWIVDT 254
            ..|.:...||.||
Human   244 TKVYNYVDWIKDT 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_001286096.1	Tryp_SPc	30..251	CDD:214473	91/236 (39%)
CG17571	NP_001286096.1	Tryp_SPc	31..254	CDD:238113	93/238 (39%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	91/236 (39%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	93/238 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8473
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920