DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17571 and Prss53

DIOPT Version :9

Sequence 1:	NP_001286096.1	Gene:	CG17571 / 35409	FlyBaseID:	FBgn0259998	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	82/303 - (27%)
Similarity:	126/303 - (41%)	Gaps:	66/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLSVVALVALAASC-HGNPGLDFP-FGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETV 67
            ::.:..|.|...:| ...||...| .|..:.||      :|:|.||: .:|.|.|.|||:....|
  Rat    15 VIVIEGLQAAQRACGQRGPGPPEPQEGNTLPGE------WPWQASVR-RQGVHICSGSLVADTWV 72

  Fly    68 LTAAHCMQSYAASEL---QVRVGSTSR---SSGGEVVTVRAFKYHEGYNSKLMINDVAIIKLSSP 126
            ||||||.:..|.:||   .|.:||..:   |.|.|.|.|.|.:..:.||.....:|:|:::|:.|
  Rat    73 LTAAHCFEKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHP 137

  Fly   127 VRQTSKIRAIELADSEAVSGTNAVVSGW------GTTC----------------FLFCS------ 163
            :..|:  ..:.........|.:...:||      |..|                ...||
  Rat   138 IVHTT--LCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALCSHCVSEL 200

  Fly   164 ----SP----DTLQKVEVDLLHYKDCAADTYNYGSDSILET-----MVCATGEK--KDACQGDSG 213
                ||    .||:.:.:.|:....|.. .||.....:|..     |:|...:.  :..||||||
  Rat   201 DSTLSPLPVSRTLRNLRLRLISRPTCNC-LYNRLHQRLLANPARSGMLCGGAQPGVQGPCQGDSG 264

  Fly   214 GPLVADNK-----LVGVVSWGSGCAWTGYPGVYADVASLRSWI 251
            ||::....     .||::|:.|.||....|.:..|:|:..||:
  Rat   265 GPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_001286096.1	Tryp_SPc	30..251	CDD:214473	74/274 (27%)
CG17571	NP_001286096.1	Tryp_SPc	31..254	CDD:238113	75/275 (27%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	75/273 (27%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030