DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17571 and PRSS53

DIOPT Version :9

Sequence 1:	NP_001286096.1	Gene:	CG17571 / 35409	FlyBaseID:	FBgn0259998	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_011544118.1	Gene:	PRSS53 / 339105	HGNCID:	34407	Length:	623	Species:	Homo sapiens

Alignment Length:	305	Identity:	83/305 - (27%)
Similarity:	122/305 - (40%)	Gaps:	74/305 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LVALAASC-HGNPGLDFP-FGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLIDSETVLTAAHC 73
            |.|...:| ...||...| .|..|.||      :|:|.||: .:|:|.|.|||:....|||||||
Human    21 LQAAQRACGQRGPGPPKPQEGNTVPGE------WPWQASVR-RQGAHICSGSLVADTWVLTAAHC 78

  Fly    74 MQSYAASEL---QVRVGSTSR---SSGGEVVTVRAFKYHEGYNSKLMINDVAIIKLSSPVRQTSK 132
            .:..||:||   .|.:||..|   |.|.|.|.|.|.:....||.....:|:|:::|:.|...|.
Human    79 FEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTP- 142

  Fly   133 IRAIELADSEAVSGTNAVVSGW---------------------------GTTCFLFCS------- 163
             ..:.........|.:...:||                           ...|..|.|
Human   143 -LCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQ 206

  Fly   164 ----------SPDTLQKVEVDLLHYKDCAADTYN-----YGSDSILETMVCATGEK--KDACQGD 211
                      :|.||:.:.:.|:....|.. .||     :.|:.....|:|...:.  :..||||
Human   207 TLAPAPSLSPAPGTLRNLRLRLISRPTCNC-IYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGD 270

  Fly   212 SGGPLVA---DNKLV--GVVSWGSGCAWTGYPGVYADVASLRSWI 251
            ||||::.   |...|  |::|:.|.||....|.:..:.|:..||:
Human   271 SGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_001286096.1	Tryp_SPc	30..251	CDD:214473	75/282 (27%)
CG17571	NP_001286096.1	Tryp_SPc	31..254	CDD:238113	76/283 (27%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	76/284 (27%)
		Tryp_SPc	43..314	CDD:214473	74/280 (26%)
		Tryp_SPc	359..>512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940