DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17571 and Klk11

DIOPT Version :9

Sequence 1:	NP_001286096.1	Gene:	CG17571 / 35409	FlyBaseID:	FBgn0259998	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001099722.1	Gene:	Klk11 / 292849	RGDID:	1308690	Length:	279	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	87/261 - (33%)
Similarity:	132/261 - (50%)	Gaps:	32/261 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLLSVVALVALAASCHGNPGLDFPFGRIVNGEDVDIENYPYQVSV-QTTKGSHFCGGSLIDSETV 67
            ::|..:||..:.....|..       ||:.|.:....:.|:||:: |.|:  ..||.:||..:.:
  Rat    31 MILRFIALALVTGHVGGET-------RIIKGYECRPHSQPWQVALFQKTR--LLCGATLIAPKWL 86

  Fly    68 LTAAHCMQSY-----AASELQVRVGSTSRSSGGEVVTVRAFKYHEGYNSKL----MINDVAIIKL 123
            ||||||.:.:     ....|:...|...|....|     :|. |.|:|:.|    ..||:.::|:
  Rat    87 LTAAHCRKPHYVILLGEHNLEKTDGCEQRRMATE-----SFP-HPGFNNSLPNKDHRNDIMLVKM 145

  Fly   124 SSPVRQTSKIRAIELADSEAVSGTNAVVSGWGTTCFLFCSSPDTLQKVEVDLLHYKDCAADTYNY 188
            |||...|..:|.:.|:.....:||:.::||||||.......|.:|:...|.::.:|:|.. .|
  Rat   146 SSPAFITRAVRPLTLSSLCVTAGTSCLISGWGTTSSPQLRLPHSLRCANVSIIGHKECER-AY-- 207

  Fly   189 GSDSILETMVCATGEK--KDACQGDSGGPLVADNKLVGVVSWGSG-CAWTGYPGVYADVASLRSW 250
             ..:|.:||:||:..|  ||:||||||||||.:..|.|::|||.. ||.|..||||..|.....|
  Rat   208 -PGNITDTMLCASVRKEGKDSCQGDSGGPLVCNGSLQGIISWGQDPCAVTRKPGVYTKVCKYFDW 271

  Fly   251 I 251
            |
  Rat   272 I 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_001286096.1	Tryp_SPc	30..251	CDD:214473	81/233 (35%)
CG17571	NP_001286096.1	Tryp_SPc	31..254	CDD:238113	82/234 (35%)
Klk11	NP_001099722.1	Tryp_SPc	50..272	CDD:214473	81/233 (35%)
Klk11	NP_001099722.1	Tryp_SPc	51..275	CDD:238113	82/234 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4330
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8948
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920