Protein Alignment CG17571 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_610109.1
• Gene: CG17571 / 35409
• FlyBaseID: FBgn0259998
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 79/264 - (29%)
• Similarity: 123/264 - (46%)
• Gaps: 30/264 - (11%)

  Fly    13 ALAASCHGNPGLDFPFG-RIVNGEDVDIENYPYQVSVQTTKGS---HFCGGSLIDSETVLTAAHC 73
            |.|..|...|..|...| ||:.|.:.....:|:.||:|...|.   |.|||:|:....|||||||
Human    59 AHAEDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHC 123

  Fly    74 MQSYAASELQVRVGSTSRSSG----GEVVTVRAFKYHEGYNSKLMINDVAIIKLSSPVRQTSKIR 134
            .:..:...:...|..|:...|    .:.:.::|...|..:..:..:||:|:..|...||....|:
Human   124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQ 188

  Fly   135 AI-------ELADSEAVSGTNAVVSGWGTTCFLFCSSPDTLQKVEVDLLHYKDCAADTYNYGSDS 192
            .|       ::.|    ..|...:||||.| ....::.:.||..||..:..:.|.::. :||. .
Human   189 PICLPFDVFQILD----GNTKCFISGWGRT-KEEGNATNILQDAEVHYISREMCNSER-SYGG-I 246

  Fly   193 ILETMVCATGEKK--DACQGDSGGPLVA---DNK---LVGVVSWGSGCAWTGYPGVYADVASLRS 249
            |..|..||..|..  |.|:|||||||:.   :.|   ::|:.|:|.||...|:||||...:..:.
Human   247 IPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQK 311

  Fly   250 WIVD 253
            |:.:
Human   312 WLTE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17571	NP_610109.1	Tryp_SPc	30..251	CDD:214473	72/242 (30%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	72/245 (29%)