DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv3 and Atp1b4

DIOPT Version :9

Sequence 1:	NP_001260675.1	Gene:	nrv3 / 35408	FlyBaseID:	FBgn0032946	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_445833.2	Gene:	Atp1b4 / 84396	RGDID:	620994	Length:	356	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	82/323 - (25%)
Similarity:	131/323 - (40%)	Gaps:	90/323 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIFTVFYQTL------------DNEKP 76
            ::||:.|....|.|||.|.:.||:.|..|||:|    ||:.|:|...|            :..||
  Rat    90 EYLWDPEKRMSLARTGQSRSLILVIYFFFYASL----AAVITLFIYMLFLAISPYMPTFTEQVKP 150

  Fly    77 KWMLDNGLIGSNPGLGFRPMPPEANVESTLVWYESSKKDNYKYWVDETSRFLKYHTYQD-LEKQN 140
                        ||:..||.....|..     :..|:.:.::.:|...:.||:  .|.| |:::.
  Rat   151 ------------PGVMIRPFAHSLNFN-----FNVSEPETWQRYVISLNGFLQ--GYNDSLQEEM 196

  Fly   141 QVNCSFEHPP-----------QDDKVCGIDFSSFSPCTA--DNNFGYHVARPCIFLKLNKIYNWI 192
            .::|    ||           :|.|.|....|....|:.  |..|||...:|||.||:|:|..:.
  Rat   197 NIDC----PPGQYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFR 257

  Fly   193 PEIYNDSKTLPDHMPEELKQHIKEKQSLRPNETNVVWVSCEGENPADVENIKARDYYPR-MGFPR 256
            ||..:..|                             |||:.:. .|..||::.:|||. ..|..
  Rat   258 PEFGDPVK-----------------------------VSCKVQK-GDENNIRSINYYPESASFDL 292

  Fly   257 YYFPF---KNIQGYIPPIVAVQFT-VETGVLINIECKAWARNINHDRSDRR--GSVHFELMVD 313
            .|:|:   .....|..|:||:.|| |.....:.::|:...:.|.:|..:.|  |.:.|.|.::
  Rat   293 RYYPYYGKLTHVNYTSPLVAMHFTDVVKNQEVPVQCQLKGKGIVNDVINDRFVGRIIFTLNIE 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv3	NP_001260675.1	Na_K-ATPase	20..307	CDD:395224	80/315 (25%)
Atp1b4	NP_445833.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..77
Atp1b4	NP_445833.2	Na_K-ATPase	90..348	CDD:395224	80/314 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	137	1.000	Domainoid score	I4756
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4445
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm9102
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11523
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.980