Protein Alignment nrv3 and ATP4B

DIOPT Version :9

• Sequence 1: NP_001260675.1
• Gene: nrv3 / 35408
• FlyBaseID: FBgn0032946
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 90/320 - (28%)
• Similarity: 134/320 - (41%)
• Gaps: 66/320 - (20%)

  Fly    18 KWEGFKKFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIFTVFYQTLDNEKPKWMLDN 82
            :.|.|:::.||.:|.|.||||.|.|..|.|:|:.||..:||.||....|..||:|...|.:  .:
Human    13 RMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDY--QD 75

  Fly    83 GLIGSNPGLGFRP-MPPEANVESTLVWYESSKKDNYKYWVDETSRFLKYHT-YQDLEKQNQVNC- 144
            .|  .:||:..|| :..|..:|   :.|..|  || :.|.|.|.....:.. |....:::.:||
Human    76 QL--RSPGVTLRPDVYGEKGLE---IVYNVS--DN-RTWADLTQTLHAFLAGYSPAAQEDSINCT 132

  Fly   145 --------SFEHPPQDDKVCGIDFSSFSPCT--ADNNFGYHVARPCIFLKLNKIYNWIPEIYNDS 199
                    ||..|......|.........|:  ||.|||:...:||..:|:|:|..::|.  |.|
Human   133 SEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPS--NGS 195

  Fly   200 KTLPD----HMPEELKQHIKEKQSLRPNETNVVWVSCEGENPADVENIKARDYYPRMG-FPRYYF 259
            ....|    ..|.||.|.::.|                              |||..| |..:||
Human   196 APRVDCAFLDQPRELGQPLQVK------------------------------YYPPNGTFSLHYF 230

  Fly   260 PF--KNIQ-GYIPPIVAVQ-FTVETGVLINIECKAWARNI--NHDRSDRRGSVHFELMVD 313
            |:  |..| .|..|:||.: ..:.....:.|.||..|.::  |:......|.|.|:|.::
Human   231 PYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv3	NP_001260675.1	Na_K-ATPase	20..307	CDD:395224	87/310 (28%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	90/320 (28%)
		immunoglobulin-like	194..291		30/127 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm8622
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4478
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.950