Protein Alignment nrv3 and ATP4B

DIOPT Version :10

• Sequence 1: NP_001260675.1
• Gene: nrv3 / 35408
• FlyBaseID: FBgn0032946
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 90/320 - (28%)
• Similarity: 134/320 - (41%)
• Gaps: 66/320 - (20%)

  Fly    18 KWEGFKKFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIFTVFYQTLDNEKPKWMLDN 82
            :.|.|:::.||.:|.|.||||.|.|..|.|:|:.||..:||.||....|..||:|...|.:  .:
Human    13 RMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDY--QD 75

  Fly    83 GLIGSNPGLGFRP-MPPEANVESTLVWYESSKKDNYKYWVDETSRFLKYHT-YQDLEKQNQVNC- 144
            .|  .:||:..|| :..|..:|   :.|..|  || :.|.|.|.....:.. |....:::.:||
Human    76 QL--RSPGVTLRPDVYGEKGLE---IVYNVS--DN-RTWADLTQTLHAFLAGYSPAAQEDSINCT 132

  Fly   145 --------SFEHPPQDDKVCGIDFSSFSPCT--ADNNFGYHVARPCIFLKLNKIYNWIPEIYNDS 199
                    ||..|......|.........|:  ||.|||:...:||..:|:|:|..::|.  |.|
Human   133 SEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPS--NGS 195

  Fly   200 KTLPD----HMPEELKQHIKEKQSLRPNETNVVWVSCEGENPADVENIKARDYYPRMG-FPRYYF 259
            ....|    ..|.||.|.::.|                              |||..| |..:||
Human   196 APRVDCAFLDQPRELGQPLQVK------------------------------YYPPNGTFSLHYF 230

  Fly   260 PF--KNIQ-GYIPPIVAVQ-FTVETGVLINIECKAWARNI--NHDRSDRRGSVHFELMVD 313
            |:  |..| .|..|:||.: ..:.....:.|.||..|.::  |:......|.|.|:|.::
Human   231 PYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv3	NP_001260675.1	Na_K-ATPase	18..307	CDD:459748	87/312 (28%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	90/320 (28%)
		immunoglobulin-like	194..291		30/127 (24%)