DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv3 and atp1b3

DIOPT Version :9

Sequence 1:	NP_001260675.1	Gene:	nrv3 / 35408	FlyBaseID:	FBgn0032946	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_989087.1	Gene:	atp1b3 / 394687	XenbaseID:	XB-GENE-485127	Length:	279	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	89/313 - (28%)
Similarity:	149/313 - (47%)	Gaps:	73/313 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FKKFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIFTVFYQTLDNEKPKWMLDNGLIG 86
            :|:|::|.::.:.:|||.||||.|||||::||..|.|.|.....|..||||:..||:. |.   .
Frog    16 WKQFIYNPQSGEFMGRTASSWALILLFYLVFYGFLAGLFTLTMWVMLQTLDDSVPKYR-DR---V 76

  Fly    87 SNPGLGFRPMPPEANVESTLVWYESSKKDNYKYWVDETSRFLKYHTYQD-LEKQNQVNCS----F 146
            |:|||..  .|..|.:|   :.:..:|..:|:.::.....||.  .|.| ::.:|.: |:    |
Frog    77 SSPGLMI--SPKSAGLE---IKFTRNKTQSYQEYIQTLHTFLT--PYNDAIQAKNDL-CAPGLYF 133

  Fly   147 EHPPQDD-KVCGIDFSSFSPCTA--DNNFGYHVARPCIFLKLNKIYNWIPEIYNDSKTLPDHMPE 208
            :...:|: |.|..:.||...|:.  ||.|||:..:||:.:|:|:|....||  .:.|
Frog   134 DQDEKDEKKACQFNRSSLGLCSGIEDNTFGYNEGKPCVIVKMNRIIGLKPE--GNPK-------- 188

  Fly   209 ELKQHIKEKQSLRPNETNVVWVSCEGENPADVENIKARDYYPRMG-FPRYYFPF---KNIQGYIP 269
                                 ::|..:    .|::..: |:|..| ....|||:   |....|:.
Frog   189 ---------------------INCTSK----TEDVNLQ-YFPENGKIDLMYFPYYGKKTHVNYVQ 227

  Fly   270 PIVAVQF-------TVETGVLINIECKA-WARNI-NHDRSDR-RGSVHFELMV 312
            |:|||:.       :::.   |::|||. .:||: |.|..|: .|.|.|::.:
Frog   228 PLVAVKIIPPPYNSSLDE---ISLECKIHGSRNLKNEDERDKFLGRVTFKVKI 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv3	NP_001260675.1	Na_K-ATPase	20..307	CDD:395224	87/306 (28%)
atp1b3	NP_989087.1	Na_K-ATPase	14..272	CDD:366001	87/306 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5426
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4563
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm9519
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080